付占立,林景辉,张春丽,胡怀湘,范岩,王荣福.18F-FDG符合线路显像在骨及软组织肿瘤复发中的诊断价值[J].中国医学影像技术,2004,20(10):1487~1489
18F-FDG符合线路显像在骨及软组织肿瘤复发中的诊断价值
Value of 18F-FDG coincidence SPECT in diagnosis of recurrent bone and soft-tissue tumors
  
DOI:
中文关键词:  脱氧葡萄糖  肿瘤  复发  转移
英文关键词:18F-fluorodeoxyglucose  Neoplasms  Recurrence  Metastasis
基金项目:
作者单位
付占立 北京大学第一医院核医学科,北京 100034 
林景辉 北京大学第一医院核医学科,北京 100034 
张春丽 北京大学第一医院核医学科,北京 100034 
胡怀湘 北京大学第一医院核医学科,北京 100034 
范岩 北京大学第一医院核医学科,北京 100034 
王荣福 北京大学第一医院核医学科,北京 100034 
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中文摘要:
      目的 评价18F-脱氧葡萄糖(FDG)符合线路显像在骨及软组织肿瘤术后局部复发和远处转移诊断中的价值。方法 18例骨及软组织恶性肿瘤术后可疑复发患者,进行32例次18F-FDG符合线路显像,显像结果与手术病理(15例次)或临床随访(17例次)结果进行对照。结果 18F-FDG符合线路显像共检出20例次局部复发中的19例次,灵敏度为95%,其中13例次接受了针对局部复发和远处转移灶的手术治疗;无复发或转移的12例次18F-FDG符合线路显像中,阴性10例次,特异性为83%;阳性预测值、阴性预测值、准确率分别为90%、91%和91%。结论 18F-FDG符合线路显像对骨及软组织肿瘤复发的诊断有较高的灵敏度和特异性。
英文摘要:
      Objective To assess the value of 18F-FDG coincidence SPECT in the detection of local recurrences and distant metastasis of bone and soft tissue tumors.Methods Thirty two 18F-FDG coincidence SPECT studies from 18 patients with clinically suspected of local recurrence and/or distant metastasis of bone and soft tissue tumors were performed. The results were correlated with histopathology findings on surgical specimens (in 15 studies) or clinical follow up data (in 17 studies).Results On a study based analysis,18F-FDG coincidence SPECT had a sensitivity of 95% (19/20), a specificity of 83% (10/12) and an accuracy of 91% (29/32). The positive predictive value and negative predictive value were 90% (19/21) and 91% (10/11), respectively. Thirteen recurrent foci detected by 18F-FDG coincidence SPECT received surgical management.Conclusion 18F-FDG coincidence SPECT is high sensitive and specific to detect local and distant recurrences of bone and soft tissue tumors.
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