| 何悦明,李铁一,卢洁,李坤成.Gd-DTPA作为肾脏CT血流灌注对比剂的动物实验研究[J].中国医学影像技术,2004,20(9):1339~1342 |
| Gd-DTPA作为肾脏CT血流灌注对比剂的动物实验研究 |
| Gd-DTPA as a CT contrast agent for assessing renal perfusion patterns in rabbits |
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| DOI： |
| 中文关键词: CT 对比剂 Gd-DTPA 肾 灌注 |
| 英文关键词:Tomography X-ray computed Contrast agent Gd-DTPA Kidney Perfusion |
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| 中文摘要: |
| 目的 探讨Gd-DTPA作为肾脏CT增强对比剂用于肾脏血流灌注研究的可行性。方法 12只新西兰白兔,分组注射Gd-DTPA或碘对比剂,CT动态扫描获得主动脉和肾脏的时间-密度曲线,计算血流灌注数值。结果 静脉注射0.5 mmol/(kg·ml) Gd-DTPA后,肾皮质增强(33.2±11.9) Hu。Gd-DTPA和碘对比剂获得的肾脏皮质、髓质血流灌注数值无明显差异。结论 Gd-DTPA能够作为X线对比剂用于肾脏增强CT检查,并用于研究肾脏血流灌注。 |
| 英文摘要: |
| Objective To evaluate the effect of Gd-DTPA as a contrast agent on the renal contrast-enhanced CT and the renal blood perfusion. Methods Twelve rabbits were examined with dynamic CT after the Gd-DTPA or Ultravist administration. Time-attenuation curves were acquired, and the renal blood perfusion was studied. Results Mean values of the renal cortical and medullary perfusion patterns in the group of Gd-DTPA were similar to that of ultravist (t'test,P>0.05). Conclusion Gd-DTPA is a possible alternative contrast agent in CT studying kidney and renal blood perfusion. |
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