张铁梅,胡大一,边红.肱动脉流量介导的舒张功能与冠心病的关系[J].中国医学影像技术,2004,20(8):1217~1219
肱动脉流量介导的舒张功能与冠心病的关系
Correlation of flow mediated dilation in the brachial artery with coronary artery disease
  
DOI:
中文关键词:  冠状动脉心脏病  肱动脉  超声检查
英文关键词:Coronary artery disease  Brachial artery  Ultrasonography
基金项目:
作者单位
张铁梅 北京天坛医院心内科,北京 100050 
胡大一 北京同仁医院心内科 
边红 北京同仁医院心内科 
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中文摘要:
      目的 探讨肱动脉流量介导的舒张功能(FMD)与冠心病的关系。方法 受试者98人,分为冠心病组(52人)和有冠心病倾向的对照组(46人)。用高分辨率超声心动图仪检测所有受检者的肱动脉FMD。结果 冠心病组患者FMD 0.05±0.01,对照组为0.09±0.04,二组间差异有显著性意义(P=0.01)。FMD与冠状动脉病变程度不相关(P>0.05)。当把FMD临界点定为10%时,诊断冠心病的敏感性为88%,特异性为71%。结论 超声检测FMD是监测冠心病的一项重要指标。
英文摘要:
      Objective To study the correlation of the flow mediated dilation (FMD) in the brachial artery with coronary artery disease (CAD) by ultrasonography. Methods Fifty two patients with CAD and 46 patients with CAD tendency underwent ultrasonography. FMD of the brachial artery was measured by high resolution ultrasonography (10 MHz) before coronary angiography. Results FMD were 0.05±0.01 in patients with CAD,0.09±0.04 in patients with CAD tendency (P=0.01).It was demonstrated that a cutoff value for detecting the presence of CAD was 10%, with sensitivity of 88%, and specificity of 71%. Conclusion FMD is a significant indicator in the diagnosis of CAD.
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