| 张皓,沈天真,陈星荣,缪竞陶.DSC MR灌注成像在胶质瘤术前分级中的价值初探[J].中国医学影像技术,2004,20(8):1193~1196 |
| DSC MR灌注成像在胶质瘤术前分级中的价值初探 |
| DSC MR perfusion imaging in the pre operation grading of gliomas |
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| DOI： |
| 中文关键词: 神经胶质瘤 磁共振成像 灌注 脑血流 |
| 英文关键词:Glioma Magnetic resonance imaging Perfusion Brain blood flow |
| 基金项目: |
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| 中文摘要: |
| 目的 评价DSC MR灌注成像在胶质瘤术前分级中的作用及价值。方法 对28例胶质瘤病人进行DSC MR灌注检查,分析不同级别胶质瘤MR灌注曲线及伪彩图像，测量肿瘤实质部分及瘤周水肿区最大rCBV值及rMTT数值并将所测量数值进行统计学处理。结果 在MR灌注曲线图像中，高级别胶质瘤实体和瘤周水肿区最大灌注处表现为高灌注；低级别胶质瘤表现为等或低灌注为主。不同级别胶质瘤实质部分和瘤周水肿区最大rCBV值之间有统计学差异(P<0.05)，各级别胶质瘤之间rMTT值无统计意义差异(P>0.05)。结论 DSC MR灌注成像对胶质瘤术前分级有临床实用价值。 |
| 英文摘要: |
| Objective To evaluate the role of dynamic susceptibility contrast MR perfusion imaging in pre operation grading of gliomas. MethodsALL 28 pre operation glioma patients (13 grade Ⅱ, 6 grade Ⅲ,and 9 grade Ⅳ) underwent conventional and MR perfusion imaging using a GE EPI sequence. The patients' raw data were transferred to workstation and processed to obtain time signal intensity curves and color perfusion maps. The maximum rCBV and rMTT values were measured in both parenchyma part and the peri tumor edema of tumor and analyzed in a personal computer by one way ANOVA method. ResultsThe perfusion maps and curves of different grade gliomas had different characteristics. The difference of maximum rCBV values among different grade gliomas was statistically significant (P<0.05) in both parenchyma part and the peri tumor edema of tumor. No statistic significance was found among rMTT values of different grade gliomas (P＞0.05).Conclusion Combined with conventional MR imaging, DSC MR perfusion imaging is useful in the preoperative grading of glioma. |
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