| 倪新初,沈钧康,陆之安,钱农,潘昌杰,荣伟良,项剑波,陈建国,龚建平,钱铭辉.0.5T MR动态增强技术鉴别良性前列腺增生症与前列腺癌的研究[J].中国医学影像技术,2004,20(8):1168~1170 |
| 0.5T MR动态增强技术鉴别良性前列腺增生症与前列腺癌的研究 |
| Differentiation of benign prostatic hyperplasia and prostate cancer with dynamic contrast enhanced 0.5T MR imaging |
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| DOI： |
| 中文关键词: 前列腺增生 前列腺癌 磁共振成像 动态对比增强 |
| 英文关键词:Prostatic hyperplasia Prostate cancer Magnetic resonance imaging Dynamic constrasted enhancement |
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| 中文摘要: |
| 目的 探讨0.5T条件下 MRI动态增强扫描对良性前列腺增生(BPH)与前列腺癌的诊断与鉴别诊断价值。方法 对BPH 40例，前列腺癌32例患者常规行MRI平扫和动态增强扫描，观察病灶动态增强特征并绘制时间信号强度曲线(SI Time曲线)。结果 前列腺癌MRI动态增强的开始时间、最大信号强度及早期强化率与BPH不同(P分别<0.01、0.05、0.01)。SI Time曲线Ⅰ型多见于BPH，Ⅱ型既可见于前列腺癌又可见于BPH，前列腺癌以Ⅲ型为主(P<0.001)。结论 0.5T条件下MRI动态增强早期强化参数及SI Time曲线类型有助于BPH与前列腺癌的诊断与鉴别诊断。 |
| 英文摘要: |
| Objective To evaluate the role of dynamic contrast enhanced MR imaging with 0.5T in the diagnosis of benign prostatic hyperplasia (BPH) and prostate cancer. MethodsTotal 72 cases suspected with BPH or prostate cancer underwent plain and dynamic contrast enhanced MR imaging, and the characteristics of contrast were described by early phase enhancement parameters and time signal intensity curves (SI Time curves). SI Time curves were classified into 3 types according to their shapes: Type Ⅰ, steady enhancement; Type Ⅱ, plateau of signal intensity, and Type Ⅲ, washout of signal intensity. After operation, all of the specimens obtained were confirmed by histopathology. Results The early phase enhancement parameters of dynamic contrast enhanced MR imaging (onset time, maximum signal intensity and early phase enhancement rate) obtained from 32 cases of prostate cancer differed from those from 40 cases of BPH (P<0.01, 0.05, 0.01), but there was a certain extent of overlap. The benign and malignant characteristics of intermediate and late periods of post contrast which were described by the SI Time curves were as follows: Type Ⅰ most appeared in cases of BPH, Type Ⅱ could be found both in BPH and prostate cancer, whereas the SI Time curves of prostate cancer were a majority of Type Ⅲ (P<0.001). Conclusion Dynamic contrast enhanced MR imaging has certain value in differential diagnosis of prostate cancer and BPH. |
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