| 万智勇,冯敢生,郑传胜,梁惠民,王精兵,张贵祥,缪竟陶.白芨微球行门脉栓塞联合肝动脉栓塞治疗兔移植性肝癌门脉癌栓的实验研究[J].中国医学影像技术,2004,20(7):1006~1009 |
| 白芨微球行门脉栓塞联合肝动脉栓塞治疗兔移植性肝癌门脉癌栓的实验研究 |
| Combined transcatheter arterial embolization and transportal bletilla microspheres injection in treatment of transplanted liver neoplasms with portal vein tumor thrombus in rabbits: a comparative experimental study |
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| DOI： |
| 中文关键词: 肝肿瘤 瘤栓,门脉,治疗 栓塞 白芨微球,碘油 动物,实验性 |
| 英文关键词:Liver neoplasms Tumor thrombus, portal vein, therapy Embolization Bletilla microspheres, iodine Animals, laboratory |
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| 中文摘要: |
| 目的 探讨以白芨微球行门脉栓塞(TPI)联合肝动脉栓塞术(TAE)对兔移植性肝癌门脉癌栓的治疗作用。方法 种植VX2瘤株的大白兔30只,随机分为三组,采用三种方法治疗,对比观察疗效。结果 对照组、TAE组及TAE+TPI组:肿瘤生长率分别为45.7%、-3.3%及-81.8%;肝内转移率分别100%、60%及0%;门脉主干癌栓的发生率分别为90%、70%及10%。结论 TAE+TPI是一种有效地防治肝癌及门脉癌栓的方法;白芨微球可能是一种较为理想的门脉栓塞剂。 |
| 英文摘要: |
| Objective To study the effect of transcatheter arterial embolization (TAE) combined with transportal Bletilla microspheres injection (TPI) in treatment of transplanted liver neoplasms and portal vein tumor thrombus in rabbits. Methods Thirty white rabbits bearing VX2 transplanted tumor were randomly divided into three groups, each group was treated with different methods and the results were comparative studied. Results The tumor growth rate (GR) of the control group, TAE group and TAE+TPI group was 45.7%, -3.3% and -81.8%, respectively. The occurrence rate of intraparenchymal metastasis was 100%, 60%, 0%, and of portal vein tumor thrombus (PVTT) was 90%, 70%, 10%, respectively. Conclusion The TAE+TPI is an effective method in prevention and treatment of liver neoplasms and PVTT. Bletilla microspheres may be a useful potential peripheral portal vein embolizing agent. |
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