薛跃辉 综述.脂质体包裹对比剂在MR的应用[J].中国医学影像技术,2004,20(6):971~974 |
脂质体包裹对比剂在MR的应用 |
Liposome carrying contrast media in MR imaging |
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DOI: |
中文关键词: 脂质体 磁共振成像 |
英文关键词:Liposome Magnetic resonance imaging |
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中文摘要: |
MR造影剂对肝脾的增强价值有限,但其被脂质体包裹后,就能作为肝脾特异性对比剂,还可用其作为血池对比剂。通过在脂质体膜上附加抗体或制成PH敏感脂质体,还可以进一步扩大脂质体的应用范围,对肿瘤的影像诊断会更加准确。本文对携带MR对比剂的脂质体的制造方式及最近的进展进行了描述,对其实用性及原理作了简单的介绍。 |
英文摘要: |
Contrast agent of MR imaging for the liver is limited, but after entrapped by liposome, it can be used as a specific contrast agent for liver and spleen, it can also be used as blood-pool contrast agent. The liposome which have antibody in its membrane and PH-sensitive liposome can be used in more fields. They can make the tumor diagnosis become more accurate. The production and development of liposome carrying contrast agent were reviewed in this article, and its utilization and principle were also introduced. |
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