| 白荣杰,韩铭钧,王立平,韩雪,魏庆堂.CT灌注成像在孤立性肺结节中的应用[J].中国医学影像技术,2004,20(6):866~869 |
| CT灌注成像在孤立性肺结节中的应用 |
| CT perfusion imaging in solitary pulmonary nodule |
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| DOI： |
| 中文关键词: 孤立性结节 肺 体层摄影术,X线计算机 局部血流 |
| 英文关键词:Solitary nodule Lung Tomography, X-ray computed Regional blood flow |
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| 中文摘要: |
| 目的 探讨CT灌注成像对孤立性肺结节(SPN)的诊断与鉴别诊断价值。 方法 对34例SPN先行薄层平扫,再行同层动态增强扫描。在动态增强时间-密度曲线基础上,测量病灶增强的最大比值(PHSPN／PTSPN)、强化峰值(PHSPN)及达到最大峰值所需的时间(PTSPN),并测量与病灶同层的主动脉峰值(PHAA)。根据以上测得数据,计算SPN增强峰值与主动脉增强峰值比(PHSPN／PHAA),SPN灌注量(ml·min－1·ml－1)=SPN增强最大比值(Hu·min-1)/动脉增强的峰值(Hu)。结果 恶性SPN和多血性良性SPN较少血性良性SPN有更高的强化峰值PHSPN和PHSPN／PHAA。而恶性SPN与多血性良性SPN的PHSPN和PHSPN／PHAA无显著差异。多血性良性SPN增强前密度明显低于恶性SPN。恶性SPN与多血性良性SPN的灌注量明显高于少血性良性SPN。结论 CT灌注成像能反映病灶的血供信息,为孤立性肺结节性质的鉴别诊断提供证据。 |
| 英文摘要: |
| Objective To evaluate the diagnostic efficacy of CT perfusion imaging in differentiating benign from malignant solitary pulmonary nodules (SPN). Methods The thin collimation CT scan and contrast enhanced scan in 15 s, 75 s, 135 s, 193 s, 251 s after administration of contrast media 100 ml (4 ml/s) were performed in 34 cases. Patterns of time-density curve (TDC) were assessed. Peak height (ie, the maximum value of the TDC, PHSPN), time of peak height (PTSPN) and ratio of peak height of the SPN to that of the aorta were measured. Perfusion was calculated from the maximum ratio of the maximum value of the SPN to PTSPN and the peak height of aorta. Results Peak height of malignant (96.1±11.6) and inflammatory (101.2±8.4) SPNs were significantly higher than that (43.5±11.6) of benign SPNs (P<0.001, P<0.01). SPN-to-aorta ratios in malignant and inflammatory SPNs were significantly higher than that in benign SPNs (P<0.001, P<0.05). No statistically significant differences in the peak height and SPN-to-aorta ratio were found between malignant and inflammatory SPNs. Precontrast density of inflammatory SPNs was lower than that of malignant SPNs (P<0.05). Perfusion values in malignant and inflammatory SPNs were significantly higher than that of the benign SPNs (P<0.01). Conclution CT perfusion provides quantitative information for SPNs' blood flow and is proved to be an applicable diagnostic methods for the differential diagnosis of SPNs. |
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