王志强,王建东,王向东,程留芳,杨云生.应用彩色多普勒超声内镜鉴别纵隔良、恶性淋巴结[J].中国医学影像技术,2004,20(5):673~675
应用彩色多普勒超声内镜鉴别纵隔良、恶性淋巴结
Colour Doppler endoscopic ultrasonography in differential diagnosis of benign and malignant mediastinal lymph nodes
  
DOI:
中文关键词:  纵隔  淋巴结  彩色多普勒  腔内超声检查  鉴别诊断
英文关键词:Mediastinum  Lymph node  Ultrasonography, colour Doppler  Endosonography  Differential diagnosis
基金项目:
作者单位
王志强 中国人民解放军总医院消化科,北京 100853 
王建东 中国人民解放军总医院消化科,北京 100853 
王向东 中国人民解放军总医院消化科,北京 100853 
程留芳 中国人民解放军总医院消化科,北京 100853 
杨云生 中国人民解放军总医院消化科,北京 100853 
摘要点击次数: 1837
全文下载次数: 806
中文摘要:
      目的 评价彩色多普勒超声内镜在纵隔良、恶性淋巴结鉴别诊断中的价值。方法 应用彩色多普勒超声内镜(CDEUS)扫查CT检查已发现有纵隔淋巴结肿大并将进行手术治疗或超声内镜引导下活检(EUS-FNA)的患者36例(手术21例,EUS-FNA 15例),记录CDEUS检查所见淋巴结的大小、部位、回声、边界及淋巴结内部有无彩色血流信号,术中或EUS-FNA时将对应部位的淋巴结逐一标记后送病理检查,以病理检查结果为金标准判别CDEUS在纵隔良、恶性淋巴结鉴别诊断中的作用。结果 CDEUS共发现纵隔肿大的淋巴结118枚,其中有彩色血流信号的淋巴结28枚,无血流信号的淋巴结90枚。术后病理检查证实有彩色血流信号的28枚淋巴结均为恶性淋巴结,良性淋巴结中无一探及彩色血流信号,但仍有31枚恶性淋巴结内,未检出彩色血流信号。CDEUS对纵隔良、恶性淋巴结诊断的特异度为100%,阳性预测值100%,阴性预测值65.5%,灵敏度47.4%。结论 彩色多普勒超声内镜在纵隔良、恶性淋巴结鉴别诊断中具有一定意义。
英文摘要:
      Objective To evaluate the clinical value of colour Doppler endoscopic ultrasonography (CDEUS) in the differential diagnosis of benign and malignant mediastinal lymph nodes. Methods CDEUS was performed in 36 patients with detected mediastinal lymph nodes by CT before operation (21 cases) or EUS guided fine needle ampilution (15 cases). Size, region, echo signal, boundary and presence/absence of colour blood flow signal within the lymph node were recorded. Corresponding lymph node was marked individually and processed for pathological examination. Pathological results were regarded as golden standard to assess the role of CDEUS in the differential diagnosis of benign and malignant lymph nodes. Results A total of 118 enlarged lymph nodes were detected in 36 patients, of which 28 lymph nodes with colour blood flow signal and 90 without. Postoperative pathological examination confirmed that 28 nodes with color blood flow signal were all malignant, and no colour blood flow signal was detected in any benign lymph node. However, there were 31 malignant lymph nodes in which detection of color blood signal was failed. The specificity, sensitivity, positive prediction value and negative prediction value of CDEUS in the differential diagnosis of benign and malignant mediastinal lymph nodes was 100%, 47.4%, 100% and 65.5% separately. Conclusion CDEUS has certain value in differential diagnosis of benign and malignant mediastinal lymph nodes.
查看全文  查看/发表评论  下载PDF阅读器