李锐,方勇飞,郭燕丽.类风湿性膝关节炎放射性滑膜切除治疗后血管翳变化的能量多普勒研究[J].中国医学影像技术,2004,20(5):758~759
类风湿性膝关节炎放射性滑膜切除治疗后血管翳变化的能量多普勒研究
Power Doppler sonography in assessment of synovial pannus of rheumatoid knee after 32P radiation synovectomy
  
DOI:
中文关键词:  能量多普勒超声  类风湿  膝关节  放射性滑膜切除
英文关键词:Power Doppler sonography  Rheumatoid  Knee joints  Radiation synovectemy
基金项目:
作者单位
李锐 第三军医大学西南医院超声科,重庆 400038 
方勇飞 第三军医大学西南医院中医科,重庆 400038 
郭燕丽 第三军医大学西南医院超声科,重庆 400038 
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中文摘要:
      目的 研究类风湿性膝关节炎32P放射性滑膜切除治疗血管翳的高频能量多普勒改变并探讨其作为疗效判定客观指标的价值。方法 用高频超声能量多普勒观察53例患者治疗前及治疗后6~12个月膝关节滑膜血管翳血流信号改变并进行半定量分析。结果 治疗前膝关节滑膜血管翳血流信号显示43例(81.13%),其中Ⅰ级14例,Ⅱ级19例,Ⅲ级10例。治疗后6~12个月,滑膜血流显示15例(28.30%),较治疗前显著减少(P<0.01),且Ⅱ级和Ⅲ级血流信号消失。 结论 高频超声能量多普勒能够敏感地显示类风湿性膝关节炎放射性滑膜切除后血管翳改变,对治疗效果的客观判定具有重要价值。
英文摘要:
      Objective To study the power Doppler sonographic changes of synovial pannus of rheumatoid knee after radiation synovectomy, and to explore its value in objective assessment of treatment efficacy. Methods High-frequency power Doppler sonography was performed in 52 patients with rheumatoid knee before and 6-12 months after 32P intra-articular injection. Synovial pannus vascularity was classified semiquantitatively. Results Power Doppler revealed blood flow in 43 patients (81.13%) before treatment, including 14 cases in grade Ⅰ, 19 in grade Ⅱ and 10 in grade Ⅲ. 6-12 months after treatment, pannus blood flow was revealed in 15 patients (28.30%), grade Ⅱ and grade Ⅲ blood flow pattern disappeared, showing a significant reduction in pannus vascularigation (P<0.01). Conclusion High-frequency power Doppler could manifest the changes of pannus vascularity accurately and sensitively in rheumatoid knee joints after radiation synovectomy. It may be a valuable method in the assessment of RA activity and in monitoring the therapeutic responses objectively.
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