张秀梅,王荣福.符合线路SPECT18F-FDG显像诊断结外淋巴瘤[J].中国医学影像技术,2004,20(4):626~629 |
符合线路SPECT18F-FDG显像诊断结外淋巴瘤 |
Application of SPECT 18F-FDG imaging with coincidence in diagnosis of extranodal lymphoma |
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DOI: |
中文关键词: 18F-FDG 符合线路SPECT 代谢显像 淋巴瘤 |
英文关键词:18F-FDG SPECT with coincidence Metabolic imaging Lymphoma |
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中文摘要: |
目的 探讨符合线路SPECT 诊断结外淋巴瘤中的临床应用价值。方法 使用美国ADAC公司生产的Vertex Plus EPIC MCD/AC SPECT/PET,对18例术前或术后的NHL患者进行18F-FDG 代谢显像。对其中9例原发和/或继发结外NHL的显像结果进行定性和半定量分析,并与同期常规影像(超声、CT)比较,结果经组织病理学证实。结果 符合线路SPECT 18F-FDG 代谢显像发现9例结外NHL有11 个18F-FDG 摄取异常增高病灶,其对结外NHL病灶探测的敏感性、特异性和准确性分别为85%(11/13) 、100%(2/2) 、 86.7%(13/15)。 CT发现6个病灶,其敏感性、特异性和准确性分别为30.8%(4/13)、100%(2/2)、 40%(6/15)。结论 符合线路SPECT 18F-FDG 代谢显像对结外淋巴瘤的诊断不失为一种有用的辅助检查方法,具有重要的临床价值。 |
英文摘要: |
Objective To investigate the clinical application value of SPECT with coincidence in the diagnosis of extranodal lymphoma. Methods Eighteen patients with NHL were performed with 18F-FDG metabolic imaging pre- and postoperation using a Vertex Plus EPIC MCD/AC from ADAC company. The findings of 18F-FDG metabolic images were analyzed in qualitative and semi-quantitative ways for nine of them who had an extranodal NHL located in primary and/or secondary organs determined histopathologically. 18F-FDG images were compared with synchronous routine images such as ultrasonography and CT. Results There were 13 lesions in 9 patients with extranodal NHL in this study. SPECT with coincidence found 11 lesions of marked increasing of FDG uptake. The diagnostic sensitivity, specificity and accuracy of extranodal NHL were 85%, 100% and 86.7%. CT found 6 lesions only. The sensitivity, specificity and accuracy of CT were 30.8%, 100% and 40%, respectively. Conclusion 18F-FDG metabolic imaging of SPECT with coincidence plays an important role in the diagnosis of patients with extranodal NHL, which has a clinical application significance. |
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