杨好意,邓又斌,毕小军,常青,刘红云,黎春雷.高分辨力超声评价扩张型心肌病患者肱动脉内皮功能[J].中国医学影像技术,2004,20(4):538~540
高分辨力超声评价扩张型心肌病患者肱动脉内皮功能
Evaluation of brachial artery endothelial function in patients with idiopathic dilated cardiomyopathy by high-resolution ultrasonography
  
DOI:
中文关键词:  血管,内皮  反应性充血  高分辨力超声  心肌病,充血性
英文关键词:Vessel, endothelium  Reactive hyperemia  High-resolution ultrasonography  Cardiomyopathy, congestive
基金项目:
作者单位
杨好意 华中科技大学同济医学院附属同济医院超声影像科,湖北 武汉 430030 
邓又斌 华中科技大学同济医学院附属同济医院超声影像科,湖北 武汉 430030 
毕小军 华中科技大学同济医学院附属同济医院超声影像科,湖北 武汉 430030 
常青 华中科技大学同济医学院附属同济医院超声影像科,湖北 武汉 430030 
刘红云 华中科技大学同济医学院附属同济医院超声影像科,湖北 武汉 430030 
黎春雷 华中科技大学同济医学院附属同济医院超声影像科,湖北 武汉 430030 
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中文摘要:
      目的 应用高分辨力超声测量扩张型心肌病患者反应性充血前后肱动脉内径的百分变化率评价肱动脉内皮功能。方法 研究对象包括21例扩张型心肌病患者和18例健康对照者。应用高分辨力超声测量静息状态下、反应性充血后、舌下含服硝酸甘油后的肱动脉内径,并计算反应性充血和硝酸甘油诱发的内径百分变化率。结果 反应性充血诱发的肱动脉内径百分变化率扩张型心肌病患者 明显低于正常人 ,硝酸甘油诱发的肱动脉内径百分变化率扩张型心肌病患者 和健康对照者 差别无显著统计学意义。结论 扩张型心肌病患者肱动脉内皮功能减低。
英文摘要:
      Objective To evaluate brachial artery endothelial function in patients with idiopathic dilated cardiomyopathy using reactive hyperemia-induced percent change in the brachial artery diameter measured by high-resolution ultrasonography. Methods Measurements of brachial artery diameter were performed by high-resolution ultrasonography during baseline, reactive hyperemia and sublingual nitroglycerin administration in twenty-one patients with idiopathic dilated cardiomyopathy and eighteen healthy subjects. Reactive hyperemia-induced and nitroglycerin-induced percent changes in brachial artery diameter were calculated. Results The percent change in the brachial artery diameter induced by reactive hyperemia in patients with idiopathic dilated cardiomyopathy was significantly less than that in healthy subjects . No significant difference could be found in percent change in the brachial artery diameter induced by sublingual nitroglycerin between the patients and the controls . Conclusion The decreased percent change in the brachial artery diameter induced by reactive hyperemia in patients with idiopathic dilated cardiomyopathy compared with the healthy subjects indicates that brachial endothelial function is impaired in patients with idiopathic dilated cardiomyopathy.
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