魏新华,龙莉玲,黄仲奎,李文美,叶伟.脑星形细胞肿瘤的MR灌注成像和病理分级对照研究[J].中国医学影像技术,2004,20(3):381~383
脑星形细胞肿瘤的MR灌注成像和病理分级对照研究
Perfusion-weighted MR imaging in preoperative assessment of histological grade of astrocytoma
  
DOI:
中文关键词:  星形细胞肿瘤  磁共振成像  灌注  病理
英文关键词:Astrocytoma  Magnetic resonance imaging  Perfusion  Pathology
基金项目:
作者单位
魏新华 湖南省衡阳市中心医院放射科,湖南 衡阳 421001 
龙莉玲 广西医科大学第一附属医院放射科 
黄仲奎 广西医科大学第一附属医院放射科 
李文美 广西医科大学第一附属医院放射科 
叶伟 广西医科大学第一附属医院放射科 
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中文摘要:
      目的 研究MR灌注成像(PWI)在脑星形细胞肿瘤术前分级中的应用价值。方法 对28例脑星形细胞肿瘤病人行MR PWI,低级别星形细胞瘤9例,间变型星形细胞瘤12例,胶质母细胞瘤7例。依次行常规MRI及MR PWI,首先得到信号强度-时间曲线,并合成相对脑血流容积(rCBV)图,计算出最大rCBV比率。结果 三组最大rCBV比率分别为(3.23±0.97), (5.23±0.33),(6.09±0.70),三组之间比较均有显著性差异。结论 MR PWI能有效地在术前评价星形细胞肿瘤的病理级别。
英文摘要:
      Objective To study the value of the MR perfusion-weighted imaging (PWI) in preoperative assessment of histological grade of astrocytoma. Methods Twenty-eight patients with astrocytomas underwent contrast material-enhanced MR PWI. All cases were divided into three groups. The final diagnoses were 9 low-grade astrocytomas, 12 anaplastic astrocytomas and 7 glioblastomas. The signal over time curve were described and relative cerebral blood volume (rCBV) maps were produced.Then,the maximal rCBV ratios were calculated. Results The maximal rCBV ratios were (3.23±0.97) in low grade astrocytomas, (5.23±0.33) in anaplastic astrocytomas, (6.09±0.70) in glioblastomas.The differences in rCBV ratio between low grade astrocytomas, anaplastic astrocytomas and glioblastomas were significant. Conclusion MR PWI is very useful in preoperative assessing astrocytomas of histological grades.
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