| 毕小军,邓又斌,杨好意,常青,向惠娟,潘敏,黎春雷.应用组织追踪法评价犬左室收缩功能的研究[J].中国医学影像技术,2004,20(3):371~374 |
| 应用组织追踪法评价犬左室收缩功能的研究 |
| Assessment of left ventricular systolic function in dogs by tissue tracking |
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| DOI： |
| 中文关键词: 组织追踪法 心室功能,左 二尖瓣瓣环位移,收缩期 |
| 英文关键词:Tissue tracking Ventricular function,left Systolic mitral annular displacement |
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| 摘要点击次数: 2049 |
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| 中文摘要: |
| 目的 应用超声心动图组织追踪法观察左室收缩功能改变对犬二尖瓣瓣环收缩期位移的影响。方法 选用11只健康杂种犬,分别在基础状态时、静脉注射多巴酚丁胺后、静脉注射心得安后以及结扎冠状动脉左前降支,发生急性心肌缺血后,用组织追踪法在心尖四腔心切面、两腔心切面及心尖长轴切面测量二尖瓣瓣环6个不同位置的收缩期位移(DS);用M型超声心动图测量二尖瓣瓣环收缩期下移距离(DM);用超声心动图Simpson法测定左室射血分数(LVEF)。结果 在改变犬心肌整体收缩功能的过程中,用组织追踪法测量的二尖瓣瓣环6个不同位置的收缩期平均位移与用M型超声心动图测量的二尖瓣瓣环收缩期平均下移距离显著相关(r=0.94, P＜0.001);同时,二尖瓣瓣环收缩期平均DS与用超声心动图Simpson法测定的LVEF显著相关(r=0.92, P＜0.001);发生急性心肌缺血时,用组织追踪法测量的二尖瓣瓣环6个不同位置的收缩期平均位移与用超声心动图Simpson法测定的LVEF也呈显著相关(r=0.78, P＜0.001),但相关性相对较低。结论 超声心动图组织追踪法测量二尖瓣瓣环收缩期位移可快速、直观、无创性地定量评价左室收缩功能。 |
| 英文摘要: |
| Objective To observe the influence of contractility on the systolic mitral annular displacement (MAD) determined by tissue tracking (TT) and to find a rapid, simple and noninvasive way in assessing LV systolic function. Methods Eleven open-chest mongrel dogs were scanned from the apical four chamber, long axis and two chamber views at baseline, after dobutamine infusion, propranolol infusion, left anterior descending coronary artery occlusion, respectively. The MAD of 6 sites from these views were measured by tissue tracking and M-mode echocardiography, respectively. Left ventricular ejection fraction (LVEF) was determined by 2D echocardiography using Simpson's rule. Results There were no significant differences among the MAD of 6 sites at baseline (P＞0.05). The MAD of 6 sites and their mean value significantly elevated after dobutamine infusion; The MAD of 6 sites and their mean value significantly decreased after propranolol infusion (P＞0.05) or occurrence of acute myocardial ischemia (P＞0.05). With the changes of contractility, mean MAD of 6 sites determined by tissue tracking were closely correlated with mean MAD determined by M-mode echocardiography (r=0.94, P＜0.001) and the left ventricular ejection fraction (LVEF) determined by 2D echocardiography (r=0.92, P＜0.001). When acute myocardial ischemia occurred, the correlation between the mean MAD determined by tissue tracking and the LVEF determined by 2D echocardiography was lower (r=0.78, P＜0.001). Conclusion Systolic MAD determined by tissue tracking correlates closely with MAD determined by M-mode and with LVEF determined by 2D echocardiography. Thus, MAD determined by tissue tracking provides a rapid, simple and noninvasive way to assess LV systolic function. |
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