| 张萍综述,高云华审校.超声微泡造影剂在基因转移中的应用[J].中国医学影像技术,2004,20(3):362~364 |
| 超声微泡造影剂在基因转移中的应用 |
| Application of ultrasound with microbbuble in gene delivery |
| |
| DOI： |
| 中文关键词: 超声 微泡 基因转移 空化效应 |
| 英文关键词:Ultraound Microbubble Gene delivery Cavication |
| 基金项目: |
|
| 摘要点击次数: 1841 |
| 全文下载次数: 880 |
| 中文摘要: |
| 大量研究表明,不仅超声照射本身可促进目的基因在体外和体内的转染与表达,而且超声介导的微泡造影剂破坏可进一步增强基因的转染率,其主要机制是空化效应。超声造影剂作为一种新型、无创的基因运载系统具有广阔的应用前景。 |
| 英文摘要: |
| Many studies showed that not only ultrasound exposure but also ultrasound-mediated microbbuble destruction can enhance gene transfer and expression in vivo and in vitro, especially the latter is more effective. Cavication is the main mechanism. Therefore, ultrasound contrast agent as an new and non-invasive vector for gene delivery holds considerable promise. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
