| 吕珂,姜玉新,蔡胜,夏宇,朱庆莉.反向脉冲谐波超声造影显像评价肝恶性肿瘤介入治疗疗效[J].中国医学影像技术,2004,20(3):335~338 |
| 反向脉冲谐波超声造影显像评价肝恶性肿瘤介入治疗疗效 |
| Liver neoplasms treated with invasive therapies:usefulness of contrast enhancement pulse-inversion harmonic US imaging in evaluating therapeutic response |
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| DOI： |
| 中文关键词: 肝脏肿瘤 介入治疗 超声检查 造影剂 反向脉冲谐波显像 |
| 英文关键词:Liver neoplasm Invasive therapy Ultrasonography Contrast media Pulse-inversion harmonic imaging |
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| 中文摘要: |
| 目的 探讨反向脉冲谐波超声造影显像评价肝恶性肿瘤介入治疗疗效的临床应用价值。方法 对10例接受介入治疗后的肝恶性肿瘤病灶进行反向脉冲谐波超声造影显像,观察病灶的血流灌注,并与造影前后病灶的彩色多普勒显像进行对照,超声检查后随访14~16个月。结果 应用反向脉冲谐波超声造影显像,本组的10例介入治疗后肝肿瘤灶血流显示率(60%)较造影前(10%)提高,且高于彩色多普勒超声造影显像方式(40%)。随访发现复发的4例中,反向脉冲谐波超声造影显像均可见血流信号(100%),彩色多普勒超声造影显像在2例中(50%)观察到血流信号,而造影前仅在1例中(25%)观察到血流信号。结论 反向脉冲谐波超声造影显像对于评估肝恶性肿瘤介入治疗疗效较传统超声显像方法更可靠,并有望成为经皮介入治疗的有效辅助工具。 |
| 英文摘要: |
| Objective To evaluate the value of pulse-inversion harmonic (PIH) sonographic imaging with a microbubble contrast agent in assessing the therapeutic response of liver neoplasms with invasive therapies. Methods Ten patients with 10 liver neoplasms underwent PIH sonographic imaging after intravenous administration of SonoVue. The enhancement of the tumor were recorded to evaluate the therapeutic response. The results of these studies were compared with those of color Doppler sonographic imaging before and after intravenous administration of SonoVue. These 10 patients were followed up for 14 to 16 months after these procedures. Results After contrast agent administration, flow signals were showed in 60% cases with PIH sonographic imaging. Whereas flow signals were showed in 10% and 40% cases separately with color Doppler sonographic imaging before and after administration. The 4 cases, showed recurrence with follow up, were all (100%) found enhancing foci with contrast enhancement PIH imaging. Only 1 (25%) and 2 (50%) cases were found flow signals separately with nonenhanced and enhanced color Doppler sonographic imaging. Conclusion The results of contrast enhancement PIH sonographic imaging were more reliable than that of conventional sonographic imaging. Preliminary data suggests that contrast enhancement PIH sonographic imaging can be a promising nonvasive technique for assessing therapeutic response. |
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