| 黄葵,勇强,李治安,孙慧,厚磊,贾妍娜,赵冬.高血压病人中血管内皮功能与左室重量指数的关系[J].中国医学影像技术,2004,20(2):253~255 |
| 高血压病人中血管内皮功能与左室重量指数的关系 |
| Relation between endothelium-dependent vascular relaxation and left ventricular mass index in hypertension |
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| DOI： |
| 中文关键词: 高血压 内皮功能 左室重量指数 超声检查 |
| 英文关键词:Hypertension Endothelial function Left ventricular mass index Ultrasonography |
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| 中文摘要: |
| 目的 探讨高血压病人血管内皮依赖性舒张功能与左室重量指数的关系。方法 高分辨力血管超声无创性检测血管内皮依赖性舒张功能:包括血流介导性舒张(FMD%即反应性充血后内径变化与静息内径比值)及反应性充血(反应性充血最大血流量与静息血流量比值);心脏超声测量舒张末期室间隔、左室后壁厚度及左室内径,计算左室重量指数(LVMI)。结果 高血压组FMD%和反应性充血均低于对照组,但无统计学差异;高血压组的LVMI显著高于对照组;高血压伴心室肥厚组FMD%及反应性充血低于非肥厚组,但无统计学差异;相关分析显示血管内皮依赖性舒张功能与LVMI临界相关。结论 血管内皮依赖性舒张功能与LVMI在高血压病生理机制上可能存在某种联系,但需更加合理的研究方法进一步考证。 |
| 英文摘要: |
| Objective To explore the association between endothelium-dependent vascular relaxation and left ventricular mass index (LVMI).Methods A non-invasive high-resolution ultrasound was used to evaluate the endothelium-dependent vascular relaxation: including FMD% and reactive hyperaemia. End-diastolic interventricular septum,posterior wall thickness and left ventricular internal dimensions were measured by echocardiography and LVMI was calculated.Results FMD% and reactive hyperaemia were lower in hypertension than in control,which was not significant; LVMI was significantly higher in hypertension than in control; FMD% and reactive hyperaemia were lower in hypertension complicating with left ventricular hypertrophy than in hypertension without left ventricular hypertrophy,which was not significant; Correlate analysis indicated that there was borderline correlation between endothelium-dependent vascular relaxation and LVMI.Conclusion Pathophysiological correlation between endothelium-dependent vascular relaxation and LVMI may exist. Further study on above discussion was needed. |
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