| 黄东,张岩,韩鸿宾.神经节细胞瘤的MRI与组织病理学对照研究[J].中国医学影像技术,2003,19(11): |
| 神经节细胞瘤的MRI与组织病理学对照研究 |
| MRI and Histologic Pathology Findings in Ganglioneuroma |
| 投稿时间：2003-09-11 |
| DOI： |
| 中文关键词: 肿瘤 神经节细胞瘤 磁共振成像 |
| 英文关键词:Neoplasms Ganglioneuromas Magnetic resonance imaging |
| 基金项目: |
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| 中文摘要: |
| 目的 评价神经节细胞瘤的MR征象及其组织病理学基础。方法 10名经组织病理学证实为神经节细胞瘤患者,行常规及动态增强MR检查,分别分析了形态学特征,信号强度以及肿瘤的动态增强形式,并与组织病理学特征相对照。结果 神经节细胞瘤的MR征象表现为长T1长T2信号。所有肿瘤的组织学检查均有被膜存在,其中5例肿瘤被膜在MR增强后的T1WI上也可被显示。这5例肿瘤T1和T2WI上涡漩状征象与组织学标本上成束的雪旺细胞及胶原蛋白相互交织的现象相对应。在T2WI上呈高信号的肿瘤在组织学上含有大量黏液样基质而细胞和纤维成分相对较少。中到高信号的瘤体含有大量的细胞和纤维成分而黏液样基质较少。在动态增强MR上除一例肿瘤呈早期增强外,其余均呈现逐渐增强影像。结论 神经节细胞瘤的MR特征与组织学特点密切相关。 |
| 英文摘要: |
| Objective To evaluate the MR findings of ganglioneuroma and to correlate MRI findings with the histologic pathology features.Methods Conventional SE and contrast-enhanced dynamic MRI were performed in 10 patients with pathologically confirmed ganglioneuroma.The morphologic features,signal intensity and dynamic enhancement pattern of the tumors were retrospectively analyzed and correlated with histologic features.Results Capsules were present in all tumors histologically and were also detected in five tumors on postcontrast T1 weighted images.A whorled appearance corresponding to interlacing bundles of Schwann cells and collagen fibers on histologic specimens was visualized in five tumors on T1 and/or T2 weighted images.Tumors with markedly high signal intensity on T2 weighted images consisted histologically of a large amount of myxoid stroma and relatively few cellular and fibrous components.Tumors with intermediate to high signal intensity consisted of numerous cellular and fibrous components and little myxoid stroma.Early enhencement was found in only one case,while other cases showed the characteristics of gradual enhencement.Conclusion The results suggest that the MR features of ganglioneuroma are well correlated with histologic findings. |
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