| 赵炳辉,陈祖望,周康荣,丁建国,张永康.MRI动态增强在肾癌诊断中的价值及其检查技术探讨[J].中国医学影像技术,2003,19(11): |
| MRI动态增强在肾癌诊断中的价值及其检查技术探讨 |
| Diagnostic Value and Scanning Technique of Renal Cell Carcinoma with DCE MRI |
| 投稿时间：2003-06-10 |
| DOI： |
| 中文关键词: 肾癌 动态增强 磁共振成像 |
| 英文关键词:Renal cell carcinoma Dynamic contrast-enhancement Magnetic resonance imaging |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨肾癌MRI动态增强特征及其诊断价值,对肾癌的MRI检查技术作初步探讨。方法 51例肾实质内占位,包括肾细胞癌38例,少或无脂肪血管平滑肌脂肪瘤4例,复杂囊肿8例,肾嗜酸性细胞瘤1例,均经1.5 T MRI平扫及动态增强检查。动态增强包括4个回合的扫描,其中皮质期根据注射对比剂开始后的时间分别界定为皮质早期(20~30 s)和皮质晚期(40~50 s)。结果 肾癌以皮质早期相对强化百分比(CNR)>1和≤1分为富血供肾癌和少血供肾癌两组,两者动态增强特征不同,MRI动态增强有助于正确分析肿瘤的强化特征,结合MRI平扫,对肾癌的检出和定性有较大价值(敏感性为97.4%,准确性为90.2%),尤其皮质早期能较好反映大多数肾癌(84.2%)的异常血供特点。结论 高场强MRI动态增强扫描有利于肾癌的检出、定性。大多数肾癌增强皮质早期与实质期结合即能显示肿瘤的异常强化特点。 |
| 英文摘要: |
| Objective To evaluate the appearance of renal cell carcinoma (RCC) on dynamic contrast-enhanced 1.5T MRI (DCE MRI) and scanning technique.Methods Fifty-one cases with renal masses, including renal cell carcinoma (n=38), complex cysts (n=8), fatless angiomyolipoma (n=4) and oncocytomas (n=1) were examined with both conventional spin echo (SE) and DCE 1.5T MR imaging, all cases were proved by pathology.The early and late cortical phases are divided by 20~30 s and 40~50 s after the contrast material administration.Results Two groups namely hypervascular RCCs and hypovascular ones were determined by the percentage of enhancement signal intensity (>1 vs ≤1).Both of them had different characteristic patterns of enhancement.It was helpful to detect and characterize RCCs by combining conventional SE and multiphase DCE MRI, its sensitivity and accuracy was 97.4% and 90.2% respectively.Especially the early cortical phase could present enhancing characteristic of most RCC (84.2%) correctly.Conclusion DCE 1.5T MR imaging is helpful to improve the rates of detection and characterization of RCC,while the early cortical and interstitial phases are necessary for diagnosing ones. |
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