| 宋月霞,王建华,刘兰燕,李路明,邢恒国.背向散射积分技术评价冠心病患者颈动脉粥样斑块的研究[J].中国医学影像技术,2003,19(10): |
| 背向散射积分技术评价冠心病患者颈动脉粥样斑块的研究 |
| Clinical Application of Integrated Backscatter in Evaluation of Carotid plaques in Patients with Coronary Artery Diseases |
| 投稿时间：2003-05-14 |
| DOI： |
| 中文关键词: 背向散射积分 颈动脉粥样斑块 冠心病 急性冠脉综合征 |
| 英文关键词:Integrated backscatter Carotid plaque Coronary artery diseases Acute coronary syndromes |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨背向散射积分(IBS)在冠心病患者颈动脉粥样斑块性质评价中的临床价值。方法 对比分析30例急性心肌梗死 (AMI组)、32例不稳定型心绞痛(UAP组)、31例稳定型心绞痛(SAP组)和28例健康志愿者(对照组)颈动脉斑块数量和性质、内中膜厚度(IMT)和斑块背向散射积分校正值(IBS%)的差别。结果 AMI组和UAP组软斑检出率明显高于SAP组和对照组,其IBS%值显著低于SAP组和对照组(P<0.001);IMT值AMI组、UAP组和SAP组显著高于正常组。结论 急性冠脉综合征患者颈动脉斑块的性质明显不同于稳定型心绞痛患者,应用IBS可以客观、定量评价颈动脉斑块性质,可能为冠心病患者危险分层和冠心病预防措施的评价提供一种新的检测手段。 |
| 英文摘要: |
| Objective To determine the clinical value of Integrated backscatter (IBS) in evaluation of carotid plaque in patients with coronary artery disease.Methods One hundred and twenty-one subjects were divided into four groups:30 with first-onset acute myocardial infarction within one week as AMI group, 32 with unstable angina pectoris as UAP group,31 with stable angina pectoris as SAP group and 28 age- and gender-matched healthy adults as control group. Two-dimensional and Integrated backscatter examination of carotid were performed and the following parameters were obtained: intima-media thickness (IMT), the numbers and the types of plaque (hard or soft), the corrected average intensity of carotid plaques (IBS%).Results The frequency of soft plaques was higher in AMI and UAP groups while the hard plaques was more frequent in SAP group. Accordingly, IBS% of carotid plaques in AMI and UAP groups was significantly lower than that in SAP group (P<0.001). Compared with the control group, IMT was significantly increased in patients with coronary artery diseases.Conclusion The IBS% of carotid plaques was significantly decreased in patients with acute coronary syndromes, indicating that the quantitative evaluation of carotid plaques by IBS may be clinically useful in risk stratification and estimation of preventive strategies in patients with coronary artery disease. |
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