| 程艳,李思进,李险峰,王进.99Tcm-N-NOET与99Tcm-MIBI心肌显像的对比研究[J].中国医学影像技术,2003,19(9):1125~1127 |
| 99Tcm-N-NOET与99Tcm-MIBI心肌显像的对比研究 |
| Comparative Study of99Tcm-N-NOET and 99Tcm-MIBI Myocardial Imaging |
| 投稿时间：2003-04-25 |
| DOI： |
| 中文关键词: 冠状动脉性心脏病 单光子发射型计算机断层照相机 99Tcm-N-NOET 99Tcm-MIBI |
| 英文关键词:Coronary artery disease Single photo emission computed tomography 99Tcm-N-NOET 99Tcm-MIBI |
| 基金项目: |
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| 摘要点击次数: 2537 |
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| 中文摘要: |
| 目的 评价99Tcm-N-NOET｛双[N-乙氧基,N-乙基(二硫代氨基甲酸脂)氮化锝](Ⅴ)｝静息心肌血流灌注显像诊断冠心病(CAD)的临床价值。方法 可疑冠心病的74例男性、12例女性(平均年龄 55.6±11.5岁)行门控静息心肌血流灌注显像和冠脉造影(将冠脉管腔狭窄≥50%定为病变血管),其中行99Tcm-N-NOET静息心肌显像44例(平均年龄55.9±11.6岁),行99Tcm-MIBI静息心肌显像42例(平均年龄55.4±11.5岁)。前者于注药后1h显像,后者于注药后1~1.5h显像。结果 99Tcm-N-NOET和99Tcm-MIBI诊断冠心病的灵敏度分别为71.4%和64.7%(P＞0.05),特异性分别为88.9%和87.3%(P＞0.05),两组间灵敏度和特异性均无显著性差异。结论 99Tcm-N-NOET与99Tcm-MIBI静息心肌血流灌注显像对诊断冠心病具有一致性 |
| 英文摘要: |
| Objective To evaluate the value of the rest techenium-99m-bis (N-ethoxy, N-ethyl-dithiocarbamato) nitride (99Tcm-N-NOET) gated SPECT myocardial perfusion imaging (GSPECT) for detecting coronary artery disease (CAD). Methods For evaluation of suspected CAD, 74 men and 12 women (mean age, 55.6±11.5years) underwent the rest GSPECT and coronary angiography(CAG, ≥50% luminal diameter stenosis was considered significant coronary stenosis).All of them underwent 99Tcm-N-NOET (n=44, mean age 55.9±11.6years) or techenium-99m sestamibi (99Tcm-MIBI, n=42, mean age 55.4±11.5years) for gated GSPECT. Rest SPECT imaging was began 1 hour after intravenous injection of 99Tcm-N-NOET or 1 to 1.5 hour after the intravenous injection of 99Tcm-MIBI at rest. Results Sensitivities of 99Tcm-N-NOET and 99Tcm-MIBI GSPECT for detecting CAD were 71.4% and 64.7%, respectively. The specificity for both imaging agents was 88.9% and 87.5%, respectively. No significant difference in sensitivities and specificities was noted for the two imaging agents(P＞0.05). Conclusion GSPECT with 99Tcm-N-NOET or 99Tcm-MIBI gives diagnostic information comparable to each other in patients undergoing rest protocal for assessment of CAD. GSPECT with 99Tcm-N-NOET is clinically feasible in detecting coronary artery disease. |
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