| 姜庆军,肖湘生,刘士远,肖体乔,陈敏.相干X线相衬成像的初步研究:离体大白鼠肝脏、肺脏成像实验[J].中国医学影像技术,2003,19(9):1116~1117 |
| 相干X线相衬成像的初步研究:离体大白鼠肝脏、肺脏成像实验 |
| Study of Synchrotron X-Ray Phase-Contrast Imaging:Experimental Imaging of Rat's Liver and Lung in vitro |
| 投稿时间：2003-03-25 |
| DOI： |
| 中文关键词: X线相衬成像 同轴轮廓成像 动物实验 |
| 英文关键词:X-ray phase-contrast imaging X-ray in-line outline imaging Animal experiment |
| 基金项目:本课题受国家自然科学基金资助(10275087/A050411)。 |
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| 中文摘要: |
| 目的 应用同轴轮廓成像原理对大白鼠离体肝脏、肺脏进行X线相衬成像实验,并与常规X线技术对比,为进一步实验奠定基础。方法 在北京正负电子对撞机国家实验室,利用同步辐射装置的插入件辐射引出的空间相干X射线,应用同轴轮廓成像原理,对大白鼠离体的肝脏、肺脏进行X线相衬成像。同时,对离体的大白鼠肺脏进行常规X线摄影,并进行对比。结果 大白鼠离体肝脏血管成像未能显示内部结构;离体肺脏的同轴轮廓成像清晰度及分辨率显著高于普通X线技术。结论 X线相衬成像从原理和实践上,其分辨率都高于常规X线技术,但尚需进一步探索和改进。 |
| 英文摘要: |
| Objective To obtain the phase-contrast films of rat's liver and lung in vitro, and to evaluate the quality and resolution of the films. Methods The rat's lung and liver were imaged with synchrotron X-rays in the principle of in-line outline imaging in vitro at synchrotron national laboratory in Beijing, then the phase-contrast films were obtained. In addition, the rat's lungs were imaged with conventional X-ray at Changzheng Hospital in Shanghai. Results The film of the rat's liver did not show the vascular sign and inner structures. But the film of the rat's lung showed a good resolution and definition, and it showed the great advantage compared with the film acquired by conventional X-ray. The structure of the lung under 100μm in diameter was differentiated well. Conclusion The X-ray phase-contrast imaging has great advantage to the conventional X-ray techniques in resolution from either principle or experiment, but it should be further exploited and there would be a long run for practice in clinic. |
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