| 陈为民,王怡,杨永明.经直肠三维超声检查和前列腺特异抗原在前列腺癌穿刺活检中的作用[J].中国医学影像技术,2003,19(6):730~732 |
| 经直肠三维超声检查和前列腺特异抗原在前列腺癌穿刺活检中的作用 |
Role of Three-Dimensional Transrectal Ultrasonography and Prostate-Specific Antigen
in the Diagnostic Biopsy of Prostate Cancer |
| 投稿时间：2003-01-15 |
| DOI： |
| 中文关键词: 前列腺癌 经直肠超声 前列腺特异抗原 穿刺活检 |
| 英文关键词:Prostate cancer Transrectal ultrasonography PSA Biopsy |
| 基金项目: |
|
| 摘要点击次数: 2409 |
| 全文下载次数: 1992 |
| 中文摘要: |
| 目的 分析经直肠超声(TRUS)和前列腺特异抗原(PSA)在前列腺癌穿刺活检中的作用,提出各种穿刺方式适用的条件,以求在减少穿刺并发症的前提下获得较高的阳性结果。方法 我院2000年4月至2001年4月行前列腺穿刺病例54例,术前因为超声检查发现前列腺异常病灶或超声检查未发现前列腺异常病灶但直肠指检前列腺较硬而均经血清PSA测定异常,经TRUS引导行病灶活检或系统6点穿刺活检。结果 31人PSA≥20ng/ml,穿刺病理阳性25例,前列腺癌的检出率为80.6%,其中TRUS发现可疑病灶(TRUS+)21例均证实为癌。23人PSA<20ng/ml,穿刺病理阳性2例,前列腺癌的检出率为8.7%。TRUS(+)3例,仅1例证实为癌。此两组病人前列腺癌的检出率差异明显(P<0.01)。结论 当超声发现高度怀疑病灶同时PSA≥20ng/ml,建议病灶穿刺;超声检查阴性而PSA≥20ng/ml且前列腺体积明显增大者宜行13点TRUS引导活检;若PSA<20ng/ml则首次活检时包扩病灶在内的6点系统穿刺较为可取。 |
| 英文摘要: |
| Objective To evaluate the role of TRUS and PSA in the prostate biopsy and suggest the selection of different biopsy method. Methods Fifty-four patients with TRUS abnormalities(TRUS+) and /or abnormal PSA level underwent TRUS-guided targeted or sextant biopsy. Results Among 31 patients with PSA≥20ng/ml, 25 were pathologic positive. The detection rate of prostate cancer was 80.6%. Cancers were confirmed in 21 TRUS(+) patients. Among 23 patients whose PSA<20ng/ml, 2 were positive. Detection rate was 8.7%. Only one of 3 TRUS(+) patients had been confirmed to have cancer. The difference of detection rate between the two groups had statistic significance (P<0.01).ConclusionWhen the patients' PSA≥20ng/ml and TRUS(+), targeted biopsy is advised. When PSA≥20ng/ml, TRUS(-) and the obvious enlargment of prostate is existed, 13-core TRUS-guided biopsy is necessary. When PSA<20ng/ml, systematic sextant biopsy including the target is preferable. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
