周青,郭瑞强,孙彬,郝力丹.高频超声监测舒降之干预颈动脉粥样硬化的临床研究[J].中国医学影像技术,2003,19(6):685~686
高频超声监测舒降之干预颈动脉粥样硬化的临床研究
High-Frequency Ultrasonic Assessment of Carotid Atherosclerotic Lesions
Involved with Cholesterol-Lowering Therapy
投稿时间:2002-10-03  
DOI:
中文关键词:  颈动脉  粥样硬化  舒降之  高频超声
英文关键词:Carotid artery  Atherosclerosis  Simvastatin  High-frequency ultrasound
基金项目:
作者单位
周青 武汉大学人民医院超声科,湖北武汉 430060 
郭瑞强 武汉大学人民医院超声科,湖北武汉 430060 
孙彬 武汉大学人民医院超声科,湖北武汉 430060 
郝力丹 武汉大学人民医院超声科,湖北武汉 430060 
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中文摘要:
      目的 评价舒降之对颈动脉粥样硬化病变的影响。 方法高频超声监测随访2年舒降之治疗组的颈动脉管壁改变。 结果 舒降之治疗2年后IMT和IMT横截面积总体呈下降趋势,IMT变化速度为 年下降0.03mm。颈动脉超声分型的变化无显著意义,但粥样斑块分型于随访前后发生了一定 的变化,差异显著(P<0.05)。结论降脂药物能减轻甚至逆转 早期动脉壁粥样病变,高频超声是首选的无创监测手段。
英文摘要:
      Objective To investigate the effects of simvastatin on carotid atherosclerotic lesions. Methods Simvastatin-treating patients were followed up 2 years by high-frequency ultrasound examination.Results After 2 years treatment, the IMT and IMT area of common carotid decreased significantly (P<0.01),and IMT decreased at a speed of 0.03mm/year. The carotid wall ultrasonic classification changed non-statistically, while the plaques in carotid changed significantly (P<0.05) after 2-year therapy. Conclusion Ultrasonic examination is the first-hand choice of monitoring the retrogression and progression of the atherosclerosis involved with drug therapy non-invasively.
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