周青,郭瑞强,孙彬,郝力丹.高频超声监测舒降之干预颈动脉粥样硬化的临床研究[J].中国医学影像技术,2003,19(6):685~686 |
高频超声监测舒降之干预颈动脉粥样硬化的临床研究 |
High-Frequency Ultrasonic Assessment of Carotid Atherosclerotic Lesions Involved with Cholesterol-Lowering Therapy |
投稿时间:2002-10-03 |
DOI: |
中文关键词: 颈动脉 粥样硬化 舒降之 高频超声 |
英文关键词:Carotid artery Atherosclerosis Simvastatin High-frequency ultrasound |
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中文摘要: |
目的 评价舒降之对颈动脉粥样硬化病变的影响。
方法高频超声监测随访2年舒降之治疗组的颈动脉管壁改变。
结果 舒降之治疗2年后IMT和IMT横截面积总体呈下降趋势,IMT变化速度为
年下降0.03mm。颈动脉超声分型的变化无显著意义,但粥样斑块分型于随访前后发生了一定
的变化,差异显著(P<0.05)。结论降脂药物能减轻甚至逆转
早期动脉壁粥样病变,高频超声是首选的无创监测手段。 |
英文摘要: |
Objective To investigate the effects of simvastatin on carotid atherosclerotic lesions. Methods Simvastatin-treating patients were followed up 2 years by high-frequency ultrasound examination.Results After 2 years treatment, the IMT and IMT area of common carotid decreased significantly (P<0.01),and IMT decreased at a speed of 0.03mm/year. The carotid wall ultrasonic classification changed non-statistically, while the plaques in carotid changed significantly (P<0.05) after 2-year therapy. Conclusion Ultrasonic examination is the first-hand choice of monitoring the retrogression and progression of the atherosclerosis involved with drug therapy non-invasively. |
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