| 邓惠兴,胡国瑛,邹保民,任予.99Tcm-ASC淋巴显像在乳癌前哨淋巴结定位中的应用[J].中国医学影像技术,2003,19(4):420~422 |
| 99Tcm-ASC淋巴显像在乳癌前哨淋巴结定位中的应用 |
| Clinical Application of 99Tcm-ASC Lymphoscintigraphy in Sentinel Lymph Node Location in Breast Cancer |
| 投稿时间：2002-10-06 |
| DOI： |
| 中文关键词: 前哨淋巴结 淋巴显像 乳腺肿瘤 |
| 英文关键词:Sentinel lymph node Lymphoscintigraphy Mammary neoplasm |
| 基金项目: |
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| 中文摘要: |
| 目的 评价99Tcm-硫化锑胶体(99Tcm-ASC) 淋巴显像对乳腺癌前哨淋巴结(SLN)的定位价值,为乳腺癌SLN活检技术提供准确的定位依据。方法 对30例乳腺癌患者行99Tcm-ASC前哨淋巴结显像,同时术中行染色法(14例)或γ探测仪探测(14例)定位SLN,并与显像体表定位结果作比较。结果 显像成功率为93.3%(28/30例);共显示SLN 43个,平均1.54枚;淋巴显像检出的SLN与染色法结果完全吻合,符合率为100%,与γ探针检测符合率为85%(12/14枚);12例SLN病理阳性的患者中8例ALN有转移,16例阴性患者中14例ALN为阴性;诊断符合率为78.6%,假阴性率为7.1%。结论 99Tcm-ASC前哨淋巴结显像体表定位可以准确显示SLN的部位、数目及淋巴引流情况,可用于指导术中乳腺癌SLN γ探测定位及活检手术。 |
| 英文摘要: |
| Objective To evaluate the clinical value of 99Tcm-ASC lymphoscintigraphy in sentinel lymph node (SLN) location in breast cancer,and to offer accurate orientation for sentinel lymph node biopsy(SLNB).Methods Thirty breast cancer patients underwent 99Tcm-ASC lymphoscintigraphy,outcomes were compared with blue dye method and γ detection probe. Results The success rate of image were 93.3%(28/30),43 SLNs were accurately located.Fourteen cases were found in complete concordance with blue dye(100%).Twelve patients were found in concordance with γ detection probe,2 cases were not detected by γ probe.Of the twelve patients with SLN metastasis,8 cases were positive in ALN.Of the sixteen patients without SLN metastasis,14 cases were negative in ALN.Diagnostic coincidence rate was 78.6%,false negative proportion was 7.1%. Conclusion 99Tcm-ASC lymphoscintigraphy can show accuarate location,number and lymphatic drainage of SLN and guide γ detection probe and SLNB. |
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