田春艳,谢敬霞.肥厚型心肌病的MR首过心肌灌注初步研究[J].中国医学影像技术,2003,19(2):170~171
肥厚型心肌病的MR首过心肌灌注初步研究
Preliminary Study of Magnetic Resonance First-Pass Myocardial Perfusion Imaging in Hypertrophic Cardiomyopathy
投稿时间:2002-08-12  
DOI:
中文关键词:  肥厚型心肌病  灌注  磁共振成像
英文关键词:Hypertrophic cardiomyopathy  Perfusion  Magnetic resonance imaging
基金项目:
作者单位
田春艳 北京大学第三医院放射科,北京 100083 
谢敬霞 北京大学第三医院放射科,北京 100083 
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中文摘要:
      目的 评价心肌首过灌注磁共振成像技术对肥厚型心肌病(HCM)心肌缺血的诊断作用。 方法 对21例肥厚型心肌病患者,行MR心脏形态学及功能学检查,并进行MR心肌灌注检查,随后对心肌灌注参数进行分析,同时对比分析心功能变化。 结果 局部心肌最大信号强度增加值(SIm)减低9例,其中合并心内膜下缺血3例;灌注阳性组与阴性组相比较,左室短轴缩短率及局部室壁增厚率明显下降。 结论 MR心肌首过灌注成像能够准确地判断肥厚型心肌病的缺血改变,磁共振成像技术可以多方面对肥厚型心肌病进行评价。
英文摘要:
      Objective To access the diagnostic value of magnetic resonance first-pass perfusion imaging in hypertrophic cardiomyopathy (HCM) with myocardial ischemia. Methods Twenty-one patients with HCM were studied with gadolinium-enhanced ultrafast,magnetic resonance first-pass imaging and cine-MRI. The parameter related to perfusion and the function information were analyzed and compared statistically. Results Maximal signial intensity increase (SIm) of 9 patients were lower; subendocardial ischemia in 3 patients was observed. Patients with a positive result showed lower left ventricular fractional shortening and left ventricular wall thicking than those of patients with a negative result. Conclusion Magnetic resonance first-pass perfusion imaging has high sensitivity in judging myocardial ischemia. MRI may be the most useful method to evaluate HCM.
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