张华宁,孙吉林,吴杰,李素敏,吴晶,赵华东,吴育锦.磁源成像对中、英文语言功能区的研究[J].中国医学影像技术,2003,19(2):161~163 |
磁源成像对中、英文语言功能区的研究 |
Chinese and English Language-Specific Cortex Mapped by Magnetic Source Imaging |
投稿时间:2002-08-12 |
DOI: |
中文关键词: 磁源成像 语言 |
英文关键词:Magnetic source imaging Language |
基金项目: |
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中文摘要: |
目的 探索通过中、英文单词刺激健康志愿者后用磁源成像(MSI)无创伤性测定语言功能区的位置。 方法 作者使用脑磁图对8例右利健康志愿者进行语言接受功能区的功能成像,在此过程中,受试者进行分别听150对中、英文单词的文字识别任务。 结果 MSI显示8例受试者中有7例左侧半球内的兴奋明显强于右侧半球,有1例双侧大脑半球内的兴奋大致相等;中、英文单词刺激的磁反应波峰的后期兴奋(刺激后300~600ms)的磁源均位于颞上回和颞中回的后部。 结论 MSI是一项有发展前途的、无创伤性的检查方法,它不但可以判断语言优势半球,而且可以判定语言功能区的位置。 |
英文摘要: |
Objective To investigate the use of magnetic source imaging (MSI) for noninvasive mapping of language-specific cortex in healthy volunteers stimulated by Chinese and English words. Methods The authors performed functional imaging of the receptive language cortex using a whole-head neuromagnetometer in 8 right-handed healthy volunteers. During MSI recordings,subjects were engaged in a word recognition task by listening 150 pairs of Chinese and English words separately. Results MSI indicated that there were significantly more activities in the left hemisphere among 7 of 8 healthy volunteers,and there were nearly equal activities in the bilateral hemisphere in the other. After stimulus of Chinese and English words separately,the sources of late activity (300-600ms poststimulus onset) were both found in temporoparietal areas,including the posterior part of the middle and superior temporal gyri. Conclusion MSI is a promising and noninvasive method not only for determining cerebral dominance for language,but also for localization of language-specific cortex. |
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