| 钱银锋,余永强,郑斐群,张诚,柏亚,陈骏.磁共振灌注成像对高级胶质瘤、转移瘤 及脑脓肿的鉴别诊断价值[J].中国医学影像技术,2003,19(2):149~151 |
| 磁共振灌注成像对高级胶质瘤、转移瘤 及脑脓肿的鉴别诊断价值 |
| A Study of the Differential Diagnostic Potential of Perfusion MR Imaging among High-Grade Gliomas,Metastatic Tumor and Abscess of Brain |
| 投稿时间：2002-07-23 |
| DOI： |
| 中文关键词: 胶质瘤 转移瘤 脑脓肿 磁共振灌注成像 |
| 英文关键词:Gliomas Metastases Brain abscess Perfusion MR imaging |
| 基金项目:本课题受安徽省自然科学基金资助(99044530)。 |
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| 中文摘要: |
| 目的 评价磁共振灌注加权成像(PWI)对Ⅲ~Ⅳ级胶质瘤、脑转移瘤及脑脓肿的诊断和鉴别诊断价值。 方法 本组31例病人行PWI,绘制出灶周区和对侧对称区的信号强度-时间曲线,计算两兴趣区最大信号强度下降百分比、相对脑血流容积(rCBV)之比值Q。并计算病变自身的rCBV。 结果 Ⅲ~Ⅳ级胶质瘤、脑转移瘤和脑脓肿的QSRR分别为1.88、0.31、0.95,QrCBV为2.61、0.26、1.01,各组Q值间具有显著统计学差异,而病变的灌注间则无统计学差异。 结论 PWI在Ⅲ~Ⅳ级胶质瘤、脑转移瘤及脑脓肿的诊断和鉴别诊断中具有重要价值。 |
| 英文摘要: |
| Objective To evaluate the potential of perfusion weighted imaging (PWI) in diagnosis and differential diagnosis among malignant glioma,metastatic tumor and abscess of brain. Methods PWI was performed in 31 patients to get signal intensity percentage-time curves of perilesion and contralarteral symmetric region,which were used to calculate maximum signal reduction ratio (SRRmax) and relative cerebrum blood volume (rCBV). The ratio Q of SRRmax and rCBV in both ROIs was calculated. In addition,SRRmax and rCBV of the lesions were calculated. Results The QSRR values were 1.88,0.31 and 0.95 in grade Ⅲ-Ⅳ gliomas,while QrCBV values in metastatic tumors and brain abscess were 2.61,0.26 and 1.01 respectively. The difference in the Q values was statistically significant among three groups,and the values of lesions had no obvious discrepancy. Conclusion PWI is very useful in diagnosis and differential diagnosis among grade Ⅲ-Ⅳ gliomas,metastatic tumors and abscess of brain. |
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