| 邓学东,沈延政,黄敏,严禹,孙勤,周轶群,徐颖.超声引导下经皮经肝穿刺微波凝固治疗肝癌的临床研究[J].中国医学影像技术,2002,18(11):1171~1173 |
| 超声引导下经皮经肝穿刺微波凝固治疗肝癌的临床研究 |
| Ultrasound-Guided Percutaneous Microwave Coagulation Therapy in Treatment of Liver Cancer: A Clinical Study |
| 投稿时间：2002-05-23 |
| DOI： |
| 中文关键词: 肝脏肿瘤 微波凝固 介入放射学 三维超声 利声显 |
| 英文关键词:Liver neoplasm Microwave coagulation Interventional radiology 3-D ultrasound Levovist |
| 基金项目:本课题获江苏省非教育系统留学回国人员科技活动B类经费择优资助。 |
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| 中文摘要: |
| 目的
在实时超声引导下将微波天线直接插入人体肝脏肿瘤,产生凝固坏死(PMCT)。评价该方法
在治疗肝脏肿瘤中的价值。方法 应用HSE-8M微波治疗仪(频率2450MHz
)
对32例患者的51个肝癌结节进行微波凝固治疗,并用Levovist(利声显)超声造影、3-D US和
实验室检查等观察疗效。结果 微波凝固治疗后,Levovist造影显示肿瘤内
血流消失或明显减少,32例中有20例原发性肝癌,其中16例AFP明显下降,一例下降近3万单
位,无严重并发症,临床疗效较满意。结论 PMCT可使肿瘤留置固化、原
位灭活,是一种安全、有效、副作用小、可供选择的肝癌非手术治疗方法;将肿瘤内血管树
主干作为凝固治疗的主要目标,可提高疗效;Levovist造影观察PMCT前后肝脏肿瘤内血流的
变化应当作为判断 PMCT疗效的金标准;3-D US成像可以非常直观地观察凝固区形态,准确
测量凝固区体积,客观评价疗效。 |
| 英文摘要: |
| Purpose In a clinical study, percutaneous microwave coagulation therapy (PMCT) was admini
stered to evaluate this method as a therapy option for liver cancer. Met
hods HSE-8M PMCT equipment was utilized at 2450 MHz in frequency. Clin
i
cally, 51 cancerous nodules of 32 patients were treated, and then the results we
re evaluated using Levovist, 3-D ultrasound, and Lab findings. Results
Clinically, after PMCT, all of 51 nodules had smaller size and disappear
ance or reduction of blood flow. AFP dropped in 16/20 patients with hepatocellula
r carcinoma (HCC). Among them, one patient's AFP had
a decrease of nearly 30 thousand units. The efficacy of PMCT was good without sev
ere complications. Conclusion ①Ultrasound-guided PMCT is one
of effective meth
ods for the treatment of liver cancer; ②Paying much attention to the coagulatio
n of main branches of tumor vessels has a better result of treatment; ③LEV
OVIST contrast should be a gold standard for evaluation of treatment efficacy; a
nd ④3-D US images accurately reflect true coagulation volumes in PMCT. |
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