| 王世宏,王金锐,刘志跃,秦林金,陈瑶.组织强度曲线评价心梗病人左室局域舒张功能[J].中国医学影像技术,2002,18(11):1103~1105 |
| 组织强度曲线评价心梗病人左室局域舒张功能 |
| Evaluation of Regional Diastolic Function in Patients with Myocardial Infarction by Tissue Intensity Curves |
| 投稿时间：2002-03-18 |
| DOI： |
| 中文关键词: 组织强度曲线 心肌梗死 舒张异常 局域心室 |
| 英文关键词:Tissue intensity curve Myocardial infarction Diastolic abnormality Regional ventricle |
| 基金项目:本课题获内蒙古自治区自然科学基金资助(20001306)。 |
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| 中文摘要: |
| 目的 探索冠心病(CAD)患者左室舒张各期局部心肌组织强度特点及其评价左室局域舒张功能的可能性。方法 对19例前壁心肌梗死病人(MI组)和28例正常对照者(NOR组)的左室心肌进行组织多普勒成像检查。记录心尖二腔动态图像,应用组织强度曲线(TIC)描记技术获取左室各节段心肌同步组织强度曲线,测量等容舒张期(IR)、快速充盈期(RF)、缓慢充盈期(SF)、心房收缩期(AC)局部心肌组织强度值(TI)及强度变化幅度,对两组结果进行对比分析。结果 NOR组在整个舒张期24/28(85.71%)例的 TI自心尖至心底呈负值增大梯度变化;MI组该规律消失,梗死节段组织强度负值明显增大。IR期:NOR组141/224(62.95%)节段由向上波群组成,TI值为-38.07±2.52dB;MI组多为水平或向下波群,TI为-46.23±2.31dB,向上波群仅有49/152(32.24%)节段,两组相比,P<0.01。 RF期:NOR组为快速向上波群, 组织强度负值在心尖较小,在心底较大;MI组波群近于水平,组织强度负值在心尖较大,在心底较小,与NOR组各节段相比,P<0.05~P<0.001。 SF期:NOR组水平或向下波群有167/224(74.51%)节段;MI组水平或向下波群有67/152(44.08%)节段, 两组相比P<0.05。AC期:NOR组多为向上波群,TI负值较小(-38.00±2.78dB);MI组多为向下波群,梗死节段负值较大(-45.37±0.14dB),两组相比P<0.05。 结论 局部心肌梗死导致整个舒张期组织强度异常。组织强度能敏感、直观地无创定量评价局部心肌舒张功能异常,对早期诊断冠心病心肌缺血,阐明心室重构可能有重要价值。 |
| 英文摘要: |
| Objective To detect the tissue intensity features of regional wall abnormalities in patients with coronary artery disease (CAD) during each diastolic period, and its possibility to evaluate regional left ventricular diastolic function. Methods Nineteen patients with anterior myocardial infarction (MI group)and 28 normal subjects (NOR group)were performed in 2-chamber-view by Doppler tissue imaging. Tissue intensity of LV segments along long axis during each diastolic phase was analyzed by off-line tissue intensity curves synchronously. Results In NOR group, TI of 24/28 (85.71%) cases showed an increasing negative value from the apex to base during whole diastolic phase; in MI group, this law disappeared and the negative value of TI in infarction segments was bigger than that of NOR. IR phase: in NOR, 141/224 (62.95%) segments were upward group waves and the TI was (-38.07±2.52)dB; In MI group, TI of only 49/152 (32.24%) segments tended to be upward in infraction segments, and their TI value was (-46.23±2.31)dB. Comparing two groups, P<0.01. RF period: in NOR group, they were upward and steep group waves and their negative values were smaller in apex and bigger in base, In MI group, the group waves of TI tended to be horizontal and their negative values were bigger in base and smaller in apex. Compared with NOR group, P<0.05-P<0.001. SF period: in MI group, 67/152(44.08%) segments were horizontal and downward group waves, compared with NOR group (167/224 segments,74.51%), P<0.05. AC period: MI group had more relatively downward group waves and bigger negative values of TI (-45.37±0.14)dB, P<0.05 by compared with NOR group (-38.00±2.78)dB. Conclusion Regional myocardial ischemia and infarction can cause significant regional diastolic wall abnormalities of tissue intensity in whole diastolic phase. Regional diastolic wall motion abnormalities can be evaluated quantitatively and synchronously with high sensitivity by TIC which has the potential value in early diagnosis of regional myocardial ischemia in CAD and clarifying ventricular reconstruction. |
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