| 詹松华,毛新清,杨振燕,郑少强,张蕾.主动脉粥样硬化斑块的CT仿真显示研究[J].中国医学影像技术,2002,18(11):1095~1097 |
| 主动脉粥样硬化斑块的CT仿真显示研究 |
| Study of Helical CT Virtual Endoscopy in Diagnosis of Atherosc lerosis |
| 投稿时间：2002-04-29 |
| DOI： |
| 中文关键词: 动脉粥样硬化 CT 仿真内镜 兔 |
| 英文关键词:Atherosclerosis CT Virtual endoscopy Rabbit |
| 基金项目: |
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| 摘要点击次数: 1978 |
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| 中文摘要: |
| 目的
探讨CT仿真(CTVE)对动脉粥样硬化病变的诊断价值。方法 15只新西兰大白兔,喂
以高脂饲料3个月,建立动脉
粥样硬化动物模型。对其主动脉进行螺旋CT增强扫描,将获得的容积数据进行CTVE重建,将
影像所见与病理结果对照进行统计学分析。结果 CTVE对
动脉粥样硬化诊断的灵敏度、特异度、假阳性率、假阴性率、阳性预测值和阴性预测值分别
为68.75%、71.43%、28.57%、31.25%、73.33%和66.67%。CTVE检查与病理检查之间具有相关
性(rs=0.327, P<0.05)。结论 CTVE对动脉粥样硬化病
变具有一定的诊断价值,具有形象直观和无创伤性的优点,可作为其
他诊断方法的补充。 |
| 英文摘要: |
| Purpose
To investigate the diagnostic value of helical CT virtual endoscopy (CTVE) for a
therosclerosis (AS). Methods In order to create the animal model
of atherosclerosis, 15 male New Zealan
d white rabbits were fed with cholesterol diet for three months. We scanned the
thoracic aorta of the model rabbit of atherosclerosis after injecting the contra
st agents and transferred the volume image data to the graphic workstation with
a virtual endoscopy software in order to reconstruct the CTVE images. The findin
gs of CTVE images were compared with those on pathological examination. Results The diagnostic sensitivity of the atherosclerosis usin
g CTVE was 68.75%, specifity 71.43%, false positive ratio 28.57%, false negative
ratio 31.25%, positive predictive value 73.33% and negative predictive value 66.
67%, respectively. A correlation was found between the findings on the CTVE imag
es and those at the examination of pathology (rs=0.327, P
<0.05). Conclusion CTVE can provide diagnostic
information for the detcting atherosclerosis and serve as a noninvasive supplemental met
hod to other diagnostic methods. |
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