| 顾蔚蓉,丰有吉,张珏华.Levovist 在彩超诊断卵巢癌盆腔复发灶的应用研究[J].中国医学影像技术,2002,18(10):1057~1060 |
| Levovist 在彩超诊断卵巢癌盆腔复发灶的应用研究 |
| Efficacy of Levovist in Color Doppler Ultrasonography of Recurrence of Ovarian Cancer |
| 投稿时间：2002-03-06 |
| DOI： |
| 中文关键词: 彩色多普勒血流显像(彩超) 超声造影剂Levovist 卵巢癌复发灶 |
| 英文关键词:Color Doppler flow imaging (CDFI) Ultrasound contrast agent Levovist Recurrence of ovarian cancer |
| 基金项目: |
|
| 摘要点击次数: 1984 |
| 全文下载次数: 1336 |
| 中文摘要: |
| 目的 评价超声造影剂Levovist对彩色多普勒血流显像(彩超
)检测肿瘤血管的增强效
应,探讨其在诊断卵巢癌盆腔复发灶中的应用价值。方法 应用彩超检查
6例卵巢癌盆腔复发
灶,比较注射Levovist前后病灶内血管显像情况以及多普勒信号增强情况,并建立ROC曲线
。同时测定其血清CA125。结果 卵巢癌复发灶造影后彩色多普勒血流信号
明显增强,并显
示特征性的血管形态,血管数目明显增多,血管扭曲度增加。ROC曲线显示:造影后多普勒
信号增强开始时间≤50s、到达高峰时间≤100s、持续时间≥550s时,复发灶的敏感性、
特异性最高。结论 Levovist的应用有助彩超更准确地评价肿瘤的血供情
况
,与妇科检查、常规彩超、血清CA125结合可早期诊断卵巢癌盆腔复发灶,为临床诊断、治
疗和随访提供一定帮助。 |
| 英文摘要: |
| Objective To assess the efficacy of ultrasound co
ntrast agent Levovist in evaluating vascularization of recurrence of ovarian cancer in pelvis. Methods Six recurrences of ovarian cancer were submitted to color Doppler
flow imaging (CDFI) before and after i.v.Levovist,and then their vascularization and enhancement of Doppler signal were compared.Receiver operator characteristic curves were
established.In addition,all patients' serum CA125 level were determined. Results After contrast,color Doppler signals in recurrences of ova
rian cancer were enhanced obviously and characteristic vessel morphology were observed.Vessel numbers
and tortuosity increased.ROC curves showed that the sensitivity and specificity
were the highest when the time to commencement was ≤50s,time to peak ≤100s and durati
on of enhancement ≥550s. Conclusion Levovist increases the i
ntensity of color Doppler signals obviously,and allows a more complete display of the vascular patte
rns of recurrence of ovarian cancer.It improves markedly the role of CDFI in di
agnosis of recurrence of ovarian cancer. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
