| 孟华,姜玉新.21-三体胎儿的孕中期超声检出[J].中国医学影像技术,2002,18(10):1051~1052 |
| 21-三体胎儿的孕中期超声检出 |
| Detection of Trisomy 21 Fetuses by Mid-Trimester Ultrasound |
| 投稿时间：2002-07-05 |
| DOI： |
| 中文关键词: 21-三体综合征 颈背部皮肤增厚 孕中期超声检查 |
| 英文关键词:21-trisomy syndrome Increased nuchal fold Mid-trimester ultrasound |
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| 中文摘要: |
| 目的 探讨产前超声检查在检出21-三体胎儿方面的作用。方法 在孕中期进行超声检查,观察胎儿生长发育,测量胎儿颈背部皮肤厚度,并除外严重胎儿畸形。结果 通过超声检查发现颈背部皮肤增厚,于孕14~21周检出了3例21-三体胎儿,其中2例母亲年龄小于35岁,且无其他超声异常表现等染色体核型检查适应证。在没有应用这一超声指标进行产前筛查的6例21-三体病例中,母亲年龄小于35岁的2例被漏诊。结论 应用颈背部皮肤增厚这一超声指标可以提高产前21-三体胎儿检出率,特别是母亲年龄小于35岁,且不合并严重畸形的病例,减少产前漏诊。 |
| 英文摘要: |
| Objective To study the mid-trimester ultrasound examination in detecting trisomy 21 fetuses. Methods At mid-trimester,ultrasound was done to observe fetal growth,to measure the thickness of nuchal fold,and to exclude the major fetal abnormalities. Results Three trisomy 21 fetuses had been detected by finding the increased nuchal fold thickness between 14 and 21 weeks.In 2 of the 3 cases the maternal age was below 35 years,without any other detectable sonographic abnormalities indicating the karyotying.While in another group of 6 trisomy 21 cases,who had not received ultrasound screening including the nuchal fold,2 trisomy 21 fetuses carried by mothers younger than 35 years old remained undiagnosed until after birth. Conclusion The detection rate of trisomy 21 fetuses can be improved by mid-trimester ultrasound finding of the increased nuchal fold thickness,especially in those cases with a maternal age less than 35 years and no major fetal abnormalities. |
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