| 付建新,李坤成,王蕊,张旭,赵富强.肝硬化患者大脑基底节和白质磁化转移率测量研究[J].中国医学影像技术,2002,18(10):1024~1026 |
| 肝硬化患者大脑基底节和白质磁化转移率测量研究 |
| Measurement Study of Magnetization Transfer Ratio of Basal Ganglion and White Matter of Cerebrum in the Patients with Liver Cirrhosis |
| 投稿时间：2002-04-03 |
| DOI： |
| 中文关键词: 肝硬化 磁共振 磁化转移率 |
| 英文关键词:Liver cirrhosis Magnetic resonance imaging Magnetization transfer ratio |
| 基金项目: |
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| 中文摘要: |
| 目的 应用磁化转移率测量对肝硬化患者头颅MRI T1加权像基底节和
大脑白质高信号
进行定量分析。方法 对22例肝硬化患者和18例健康成人志愿者行MRI扫描
,并对苍白球、壳
核、尾状核头、丘脑和大脑三角区白质5个部位行磁化转移率的测量和计算。
结果 15例肝硬
化患者T1加权像可见基底节区信号增高,7例未见信号明显异常。在苍白球、壳核和三角区
脑白质部位,肝硬化患者与正常人的磁化转移率的差别有高度统计学意义。经单因子判别分析
发现,苍白球的磁化转移率测量值鉴别肝硬化患者与正常人的敏感性、特异性和准确性最高
。结论 肝硬化患者基底节和脑白质磁化转移率降低。 |
| 英文摘要: |
| Objective To quantitatively analyze magnetization
transfer ratios of basal ganglion and white matter of cerebrum,which were detected as high signal int
ensity on T1 weighted images,in the patients with liver cirrhosis.
Methods Twenty-two patients with liver cirrhosis and 18 healthy adult volunteers were examined by MRI and the magnetization transfer ratios were measured and calculated in five dif
ferent regions including globus pallidus,putamen,head of caudate nucleus,thal
amus and white matter of trigone of cerebrum. Results The magnet
ization transfer ratios of patients with liver cirrhosis were significantly lower than those o
f normal subjects.By single factor discriminant analysis,the sensibility,specificity and accuracy of the value of magnetization transfer ratios in globus pallidus were believed to be the highest. Conclusion Of patients with liver cirrhosis,lower magnetization transfer ratios can be found in basal ganglion and white matter of cerebrum. |
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