| 朱贤胜,高云华,杨未晓,夏红梅,王晓燕,陈林.二次谐波触发显像声学造影评价急性心肌缺血的实验研究[J].中国医学影像技术,2002,18(9):855~856 |
| 二次谐波触发显像声学造影评价急性心肌缺血的实验研究 |
| Assessment of Acute Myocardial Ischemia Contrast Ultrasonography by Intermittent Harmonic Imaging |
| 投稿时间：2002-01-10 |
| DOI： |
| 中文关键词: 氟碳声学造影剂 二次谐波触发显像 急性心肌缺血 |
| 英文关键词: Perfluorocarbon ultrasound contrast agent Intermittent harmonic imaging Acute myocardial ischemia |
| 基金项目: |
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| 中文摘要: |
| 目的 采用二次谐波触发显像超声造影评价急性缺血心肌血流灌注。方法 对10只犬急性心肌缺血模型用自制的白蛋白氟碳气体声学造影剂进行心肌声学造影,测量心肌灌注缺损面积,与心肌病理染色对照。结果 造影后正常心肌回声显著增强。缺血心肌呈现灌注缺损。缺损面积与心肌病理染色测值相关良好。结论 自制的声学造影剂安全有效,能用于动物心肌缺血的实验研究。 |
| 英文摘要: |
| Objective To assess the perfusion of acute myocardial ischemia with ultrasound contrast agent by intermittent harmonic imaging. Methods Transvenous MCE in 10 LAD ligated, acute myocardial ischemia dogs model with self-made perfluorocarbon ultrasound contrast agent was studied with measuring the defect area and comparing that with pathologic stain. Results After transvenous MCE, the visual enhancement of myocardium was markedly improved before LAD ligated,but hadn't any change after LAD ligated.The area of ischemia had an excellent correlation with that by pathologic stain. Conclusion The self-made perfluorocarbon ultrasound contrast agent is safe, and can be used to assess the acute myocardial ischemia in animal. |
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