| 金真,徐世勇,张磊,薛贵,曾亚伟,费军,王宗烨,谭力海.学龄儿童中文认知任务的磁共振脑功能成像研究[J].中国医学影像技术,2002,18(8):739~742 |
| 学龄儿童中文认知任务的磁共振脑功能成像研究 |
| fMRI Study in School Children Using Chinese Cognitive Task |
| 投稿时间：2002-01-11 |
| DOI： |
| 中文关键词: 磁共振,脑功能成像 儿童 认知 中文 |
| 英文关键词:fMRI Children Cognition Chinese |
| 基金项目:本研究受国家攀登计划资助(95-专-09)。 |
|
| 摘要点击次数: 2986 |
| 全文下载次数: 1148 |
| 中文摘要: |
| 目的 使用磁共振脑功能成像技术在学龄儿童中进行脑认知科学研究。 方法 使用单次激励平面回波梯度扫描序列和组块设计,对8名小学在读学生(年龄10~12岁)进行了中文同音字和真假字判断任务的血氧水平依赖对比成像。结果 8名小学生均能配合完成扫描。其中1名在扫描过程中有显著头动,所获图像因运动伪影不能使用。其余7名能保持头部位置稳定,图像资料经后处理获清晰脑激活图。 结论 该年龄组儿童已形成语言优势半球,在完成中文认知任务时显示出与成人相似的激活脑区。多数儿童可很好配合完成实验。鉴于儿童好动的特点,在设计实验时应考虑增加被试者人数并注意避免扫描时间过长。 |
| 英文摘要: |
| Objective To probe the possibility of performing functional MRI research in school children using cognitive task. Methods BOLD fMRI experiments using single-shot GE-EPI scan sequence were performed on 8 school children aging from 10 to 12 years. Two block designed Chinese cognitive tasks were devised,one based on homophone decision and the other on character decision. Results All the school children passed through the experiments. One of them had severe head motion during the scan,whereas the other seven children co-operated very well. Averaged brain activation map had been obtained after data postprocessing. Conclusion fMRI experiments using cognitive task could be performed successfully in school children above the age of 10-years-old.The predominant hemisphere for language has been developed in this age group,and the results suggested that the children have the similar brain activation mode comparing with adults. Due to the hyperactive nature of children,attention should be given to the scan duration.More subjects are needed when design a fMRI research in a pediatric group. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
