| 张梅,张运,谈红,高月花,张园园,朱媛媛.动脉粥样硬化与肾素血管紧张素系统及纤溶系统的关系[J].中国医学影像技术,2002,18(1):49~50 |
| 动脉粥样硬化与肾素血管紧张素系统及纤溶系统的关系 |
| Renin-Angiotension System and Fibrinolysis System in Atherosclerosis |
| 投稿时间：2001-08-19 |
| DOI： |
| 中文关键词: 肾素血管紧张素系统 纤溶系统 超声检查 动脉粥样硬化 |
| 英文关键词:Renin-Angiotension system Fibrinolysis system Ultrasonography Atherosclerosis |
| 基金项目:卫生部优秀青年人才专项基金资助(97037)。 |
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| 摘要点击次数: 1900 |
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| 中文摘要: |
| 目的 探讨动脉粥样硬化斑块与肾素血管紧张素系统(RAS)和纤溶系统之间的关系。方法 根据超声检查和冠状动脉造影将78例受试者分为正常组(A组)和动脉粥样硬化组(B组)。检测血浆血管紧张素Ⅱ、醛固酮、纤溶酶原激活物及纤溶酶原激活物抑制剂。结果 A组和B组Ang II分别为(32.68±13.85)pg/ml和(36.96±30.2)pg/ml, Ald分别为(0.21±0.06)pg/ml和(0.24±0.04)pg/ml,PAI-1分别为(0.51±0.17)AU/ml和(0.59±0.14)AU/ml,两组测值均存在显著性差异(P<0.05);t-PA分别为(0.33±0.12)IU/ml和(0.35±0.15)IU/ml(P>0.05)。结论 动脉粥样硬化斑块形成患者血液中的RAS和纤溶系统分泌异常。 |
| 英文摘要: |
| Objective To explore the relationship between the atherosclerosis and renin-angiotension system or fibrinolysis system. Methods The association between plasma levels of angiotension II (AngII), aldosterone (Ald),tissue plasminogen activator (t-PA),or plasminogen activator inhibitor type-1 (PAI-1) were investigated. Results The plasma levels of AngII, Ald and PAI-1 were significantly higher in group B than those of group A (P<0.05). There was no significant difference in t-PA between the two groups (P>0.05). Conclusion The patients with atherosclerotic plaque exist abnormality of function of renin-angiotension system or fibrinolysis system. |
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