| 李立伟,金泉,马璐娜,刘京璇.肝癌经动脉栓塞化疗后FDG PET显像的临床价值 ——附10例FDG PET和CT结果对照[J].中国医学影像技术,2001,17(11):1074~1075 |
| 肝癌经动脉栓塞化疗后FDG PET显像的临床价值 ——附10例FDG PET和CT结果对照 |
| Clinical Value of FDG PET Imaging in Monitoring Hepatocellular Carcinoma after Chemoembolization——Compared FDG PET with CT in 10 Cases |
| 投稿时间：2001-03-20 |
| DOI： |
| 中文关键词: 肝癌 栓塞化疗 FDG PET CT |
| 英文关键词:Hepatocellular carcinoma Chemoembolization FDG PET CT |
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| 中文摘要: |
| 目的 探讨核医学影像诊断技术——FDG PET在中晚期肝癌栓塞化疗后随诊中的临床价值,并着重比较FDG PET与CT在判断介入治疗后局部肿瘤坏死及残留状况方面的互补作用。方法 10例临床确诊的肝癌患者,术前CT或MRI示肿瘤短轴均大于4cm,经栓塞化疗后6~10个月同期行FDG PET和CT检查,并采用双盲法将FDG PET与CT结果进行比较。结果 10例CT扫描结果显示,4例肿瘤内碘油分布密集,3例肿瘤内碘油分布稀疏,3例肿瘤内碘油短期内排空;PET显示其中6例肿瘤内碘油分布稀疏或碘油短期内排空者局部肿瘤内及周边区域均有FDG明显浓聚的病变,4例肿瘤内碘油分布密集者,FDG PET均显示肿瘤边缘部位可见到不规则的放射性分布浓聚现象。结论 中晚期肝癌栓塞化疗后病灶边缘部分多有肿瘤存活或残留,但CT检查不能准确判断这一现象,而FDG PET在准确定位肿瘤残留病灶方面正好弥补了CT扫描的不足。 |
| 英文摘要: |
| Purpose This article discussed the clinical value of nuclear imaging techniques (FDG PET ) to monitor and to define tumors residue or recurrences from treatment effects for hepatocellular carcinoma after chemoembolization. And in which comparisons of FDG PET with CT scan Results were addressed specifically for clinical follow-up. Methods We studied our initial experience with 10 cases of hepatocellular carcinoma within 6 months after chemoembolization. All of whom were imaged using FDG PET and CT scan in same period. The Results of FDG PET were prospectively evaluated and compared with CT results. Results FDG PET scans depicted all cases with tumors residue or recurrences especially located in peripheral zone of lesions based on significantly increased FDG metabolism. In these cases, CT showed iodine dense distribution, less dense distribution and iodine vacuolated within two months in 4 cases, 3 cases and 3 cases. Conclusion For most cases of hepatic carcinoma after chemoembolization, there was a tendency for tumor residues in peripheral zone of lesions. FDG PET was superior than CT scans in characterizing and monitoring lesions for differentiating residue and recurrent disease from treatment effects in post-chemoembolization hepatic carcinoma. |
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