| 邹德环,莫耀溥,佘立群,殷青云,李含秋,朱旭生,焦晓风,纪平.脑血流灌注断层显像对精神分裂症的诊断价值研究[J].中国医学影像技术,2001,17(10):955~957 |
| 脑血流灌注断层显像对精神分裂症的诊断价值研究 |
| The Diagnostic Value Study of the Brain Perfusion SPECT Imaging in Schizophrenia |
| 投稿时间：2001-03-20 |
| DOI： |
| 中文关键词: 精神分裂症 脑 局部血流 断层摄影术 发射型计算机 单光子 |
| 英文关键词:Schizophrenia Brain Regional blood flow Tomography Emission computed Single photon |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨精神分裂症脑血流灌注断层显像的特点及其临床价值。方法 对22例未经治疗的精神分裂症患者进行 99Tcm-ECD SPECT脑血流灌注显像,同时测定各区与同侧小脑的放射性摄取比值。8例于治疗后进行复查。结果 22例未经治疗精神分裂症患者脑血流减低发生率为82%(18/22)。精神分裂症组右额叶、右顶叶、右颞叶及扣带回放射性摄取比值显著低于正常对照组(P<0.01或P<0.05)。8例精神分裂症患者治疗前共有16处放射性减低区,治疗后仅有8处。结论 脑血流灌注断层显像对精神分裂症的辅助诊断和疗效监测有临床价值。 |
| 英文摘要: |
| Objective To investigate the characteristics and clinical value of brain perfusion SPECT imaging in schizophrenia. Methods A group of 22 never-treated patients with schizophrenia underwent 99Tcm-ECD brain SPECT imaging. The radioactive uptake ratio of the region were calculated. And 8 patients reexamined after neuroleptic treatment. Results The Results showed that 82%(18/22)of the 22 never-treated schizophrenics showed decreased regional cerebral blood flow. The radioactive uptake ratio of the schizophrenia group of right frontal lobe,right parietal lobe,right temporal lobe and gyrus cinguli was significantly lower than that of the normal group(P<0.01 or P<0.05). There were 16 decreased regions in 8 patients with schizophrenia before treatment and only 8 decreased regions left after treatment.The radioactive uptake ratio of right frontal lobe and right temporal lobe was significantly higher after treatment than before treatment. MConclusion The brain perfusion SPECT imaging have clinical value in helping to diagnose schizophrenia and predicting the curative effect. |
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