| 马云川,张琳瑛,苏玉盛,李德鹏,尚建文.18F-FDG PET 显像寻找转移瘤原发灶初步应用[J].中国医学影像技术,2001,17(6):571~572 |
| 18F-FDG PET 显像寻找转移瘤原发灶初步应用 |
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| 投稿时间：2001-01-15 |
| DOI： |
| 中文关键词: 18F-脱氧葡萄糖 正电子发射断层显像 转移性肿瘤 原发灶 |
| 英文关键词:18F-Fluorodeoxyglucose PET Metatsatic tumors Primary foci |
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| 中文摘要: |
| 目的利用PET寻找转移瘤原发灶，探讨其影像特征和应用价值。方法应用18F-FDG PET 于15例病人，10例经活检或手术发现肿瘤转移灶，3例胸腔穿刺发现肿瘤细胞，2例头颅MRI提示颅内转移瘤。采用PET胸腹部显像和标准化摄取值（SUV）进行评价。结果12例病人于临床发现的肿瘤转移灶部位可见明显或中度示踪浓聚，SUV 2.93±0.33；3例胸腔积液病人呈片状示踪分布。14例病人经PET显像发现肿瘤原发灶，3例位于肝脏、2例位于乳腺、9例位于肺脏。转移灶与原发灶的显影类型分为三种：9例转移灶明显显影，原发灶也明显显影；2例转移灶中度显影，原发灶轻度显影；3例胸腔积液处片状示踪分布，原发灶明显显影。但有1例MRI诊断颅内转移瘤的病人，PET显像未能找到原发灶，经半年随访观察尚未发现其它肿瘤灶。结论应用18F-FDG PET 显像寻找转移瘤原发灶是一种简便、快速、无创、灵敏的方法，其准确度达90%以上，可作为解决此类问题的首选方法。 |
| 英文摘要: |
| Purpose Using 18F-FDG PET to detect primary foci of metastatic tumors. Methods 18F- FDG PET scan on the chest and abdomen was performed in 15 patients who were examined by biopsy, operation or brain MRI and proven to suffer from metastatic tumors at supraclavicular fossa, axillary fossa and brain. The standard uptake value (SUV) was also applied to help evaluation. Results According to the relationship between metastatic tumors and their primary foci, the imaging patterns can be classified into three types:①Both metastatic and primary tumors had high uptake of FDG in 9 cases; ②Metastatic tumors concentrated FDG markedly otherwise the primary foci only slightly in 2 cases; ③Diffuse radioactivity distribution at pleural cavity and limited uptake at primary foci in 3 cases. 14 of 15 patients were clearly found where the primary tumors located. There was no defined lesion in body imaging with PET for 1 patient who had positive finding in brain MRI and no other lesions appeared in half a year follow up. Conclusion Whole body 18F-FDG PET imaging is a sensitive and accurate method. |
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