董海波,戴嘉中,蔡佩武,沈天真,董亚非.H磁共振波谱在颅脑转移瘤中的应用[J].中国医学影像技术,2001,17(3):213~215 |
H磁共振波谱在颅脑转移瘤中的应用 |
H Magnetic Resonance Spectroscopy in the Diagnosis of Brain Metastasis |
投稿时间:2000-08-24 |
DOI: |
中文关键词: 颅脑转移瘤 1 H磁共振波谱 代谢 |
英文关键词:Brain metastasis 1 H MR spectroscopy Metabolite |
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中文摘要: |
目的 结合MRI探讨1 H磁共振波谱(1 H MRS)在颅脑转移瘤中的应用价值。 方法 选择32例经临床确诊为颅脑转移瘤的患者,进行MRI及1 H MRS检查。每例均行肿瘤区与健侧相应部位对照研究。 结果 32例1 H MRS均表现为明显增高的胆碱(Cho)峰,肌酸(Cr)峰下降甚至消失,无氮乙酰门冬氨酸(NAA)峰,Cho /Cr比值升高。11例出现乳酸(Lac)峰,15例出现脂质(Lipid)峰。 结论 1 H MRS可作为诊断本病的重要补充。 |
英文摘要: |
Purpose To evaluate 1 H magnetic resonance spectroscopy (1 H MRS)in the diagnosis of metastatic brain tumors with magnetic resonance imaging(MRI). Methods 32 cases diagnosed as brain metastases clinically had MRI and 1 H MRS examination . Each case had single voxel MR spectroscopy simultaneously both in the lesion's region and the contralateral side. Results 32 cases of 1 H MRS exhibited specific spectral peaks including prominent choline-containing compounds (Cho), decreased or absent total creatine (Cr), absent acetylaspartate(NAA) the metabolic ratio showed significantly increased Cho/Cr; 11cases showed abnormal lactate (Lac). 15 cases exhibited abnormal Lipid. Conclusion 1 H MRS can improve diagnostic accuracy of brain metastasis. |
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