| 刘嵘,王建华,颜志平,周康荣,邵国良,钱晟,罗剑均.不同介入方法治疗兔VX-2 肝肿瘤模型疗效的螺旋CT 评价[J].中国医学影像技术,2000,16(11):935~937 |
| 不同介入方法治疗兔VX-2 肝肿瘤模型疗效的螺旋CT 评价 |
| Therapeutic Effect of Different Interventional Methods on Hepatic Tumor of Rabbits BearingVX-2 Tumor :An Experimental Study Evaluated with Spiral CT |
| 投稿时间：2000-04-13 |
| DOI： |
| 中文关键词: 兔,动物模型 螺旋CT 介入治疗 疗效 评价 |
| 英文关键词:Rabbit/ Animal model Spiral CT Interventional therapy Therapeutic effect Evaluation |
| 基金项目:本课题受系“九五”国家医学科技攻关项目( 962907203201) 。 |
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| 中文摘要: |
| 目的用螺旋CT 评价不同介入方法治疗兔VX-2 肝肿瘤疗效。方法24 只兔分为三组,单纯灌注化疗
7 只、化疗性栓塞8 只、生理盐水9 只。分别于介入术前、术后1 周、术后2 周行螺旋CT 扫描,计算不同介入治疗后
肿瘤增长率。结果单纯灌注化疗、化疗性栓塞、生理盐水治疗后1 周肿瘤平均增长率分别为90.88 %、75.45 %、
350.96 %。术后2 周肿瘤平均增长率分别为283.49 %、237.99 %、845.43 %。结论化疗性栓塞治疗兔VX-2 肝肿
瘤疗效优于单纯灌注化疗,单纯灌注化疗优于生理盐水。螺旋CT 扫描是评价兔VX-2 肝肿瘤介入治疗的理想方
法。 |
| 英文摘要: |
| Purpose To evaluate the therapeutic effectiveness of different interventional methods on the rabbits bearing
VX-2 hepatic tumor by spiral CT. Methods 24 rabbits bearing the VX-2 hepatic tumor were divided into three groups :
transcatheter artery infusion ( TAI) with chemical agents ( n = 7) ,transcatheter artery embolization ( TAE) used lipiodol
plus chemical agent ( n = 8) ,019 % physiological saline therapy ( n = 9) . Sprial CT scan the hepatic tumors of the rabbits
was performed pre-therapy one and two weeks after interventional therapy. The growth rate of tumors was calculated to evaluate the therapeutic effectiveness. Results The growth rate of tumors of the three groups were 90188 % ,75145 % ,
350196 % respectively one week after interventional therapy ,and the growth rate of tumors were 283140 % ,237199 % ,
845143 % respectively two weeks after therapy. Conclusion The therapeutic effectiveness of TAE is superior to that of
TAI ,the therapeutic effectiveness of TAI is superior to that of physiological saline therapy. Hepatic spiral CT of rabbit bearing VX-2 tumer is useful in the assessment of the therapeutic effect after interventional therapy. |
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