卢文甫,林海丽,王爱敏,王鲁宁.进行性核上性麻痹[J].中国医学影像技术,2000,16(4):276~278
进行性核上性麻痹
Progressive Supranuclear Palsy
投稿时间:1999-09-22  
DOI:
中文关键词:  进行性核上性麻痹  临床表现  磁共振成像
英文关键词:Progressive supranuclear plasy  Clinical manifestation  MRI
基金项目:
作者单位
卢文甫 北京解放军总医院南楼脑系科,北京 100853 
林海丽 北京解放军总医院病案科,北京 100853 
王爱敏 河南许昌市公疗医院 
王鲁宁 北京解放军总医院南楼脑系科,北京 100853 
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中文摘要:
      目的 为提高进行性核上性麻痹(progressive supranuclear palsy ,PSP) 诊断的正确性。方法 报导分析例经临床和MRI 证实的PSP。结果 核上性眼肌麻痹,向下凝视,反复向后跌到,假性球麻痹,少动,强直,中轴肌张 力异常,颈部过伸,MRI 示中脑萎缩为PSP 的特点。结论 根据典型的临床表现和MRI 特点,在排除其他病时,生 前诊断PSP 是可能的。
英文摘要:
      Objective Our purpose was to improve the accuracy of the clinical dignosis of progressive supranuclear palsy (PSP) in life. Methods Two cases of PSP dignosed by clinical observations and MRI were analysed. Results PSP was characterised by supranuclear ophthalmoplegia ,particularly affecting downgaze , repeatedly falling backwards , Pseudobulbar palsy ,bradykinesia and rigidity ,axial dystonia ,stiffening and extension of the neck ,atrophy of the brainstem indicated by MRI ,especially in the midbrain. Conclusion The autmortem diagnosis of PSP might be possible on the basis of clinical manifestations and MRI results ,other neurological disease should be ruled out .
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