| 关长群,周怀伟,李爱娟,冯新莉,孙文利,魏学忠,薛洪利.颅内混合瘤的影像表现与病理-超微结构和免疫组化研究[J].中国医学影像技术,2000,16(4):273~275 |
| 颅内混合瘤的影像表现与病理-超微结构和免疫组化研究 |
| Study of Image and Pathology Ultrastructure and Immunohistochemistry in Intracranial Mixed Tumor |
| 投稿时间：1999-10-15 |
| DOI： |
| 中文关键词: 颅内混合瘤 影像 病理超微结构 免疫组化 |
| 英文关键词:Intracranial mixed tumor Image Pathology ultrastructure Immunohistochemistry |
| 基金项目: |
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| 摘要点击次数: 1430 |
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| 中文摘要: |
| 目的 提高对颅内混合瘤的CT、MRI 表现与病理相关知识的认识。方法 12 例经CT、MRI 检查及手
术光镜诊断,其中5 例作透射电镜肿瘤超微结构和免疫组化染色检查肿瘤相关抗原( GFAP、Vimentin、S2100 、FV Ⅲ因
子) 。结果 脑膜瘤和胶质母细胞瘤5 例,脑膜瘤和垂体瘤2 例,胶质母细胞瘤和脑膜瘤、垂体瘤和脑膜瘤、胶质母细
胞瘤和血管母细胞瘤、胶质母细胞瘤和血管内皮瘤、胆脂瘤和脑膜黑色素瘤各1 例。胶质母细胞瘤GFAP 强阳性,S100 弱阳性;脑膜瘤Vimentin 弱阳性,血管母细胞瘤和血管内皮瘤强阳性。结论 CT、MRI 应结合临床上病程短,发
展快等特点诊断本肿瘤。 |
| 英文摘要: |
| Purpose To evaluate the knowledge of CT ,MRI features and pathology in intracranial mixed tumor. Methods 17 cases were studied with CT ,MRI and histopathology. Ultrastructure and tumor antigens ( GFAP ,Vimentin ,S-100
and Factor FV Ⅲ) were observed by transmission electron microscope and immunoh istochemistry in 5. Results Operative
pathological diagnose as follows :mixed tumor of meningioma with glioblastoma in 5 ,meningioma with pituitary tumor in 2 ,
glioblastoma with meningioma ,pituitary tumor with meningioma ,glioblastoma with angioblastoma ,glioblastoma with angioendothelioma ,cholesteatoma with melanoma in 1 , respectively. Strong positive of GFAP and weak positive of S-100 were
showed in glioblastoma ,weak positive of Vimentin in meningioma , strong positive of Vimentin in angioblastoma and angioendothelioma. Conclusion The diagnosis should be made when CT and MRI were combined with clinical features of
short disease history and fast growth. |
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