| 刘月洁,张彤,张颖,任萍,凌广花,舒京敏,单诗山,李建国.应用彩色多普勒超声评价肱动脉血管内皮功能的研究[J].中国医学影像技术,2000,16(3):0234~236 |
| 应用彩色多普勒超声评价肱动脉血管内皮功能的研究 |
| The Evaluation of Brachial Artery Endothelial Function with Color Doppler Flow Imaging |
| 投稿时间：1999-10-04 |
| DOI： |
| 中文关键词: 彩色多普勒超声 肱动脉 血管内皮功能 |
| 英文关键词:Color Doppler flow imaging Brachial artery Endothelial function |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨彩色多普勒超声(CDFI) 评价肱动脉血管内皮功能的临床应用及其意义。方法 对30 例原
发性高胆固醇血症(PHC) 患者给予辛伐他汀(SVT) 治疗8 周,用CDFI 测定治疗前后反应性充血时和含服硝酸甘油
后肱动脉内径的变化。结果 PHC 患者SVT 治疗前反应性充血时肱动脉内径的扩张程度为3138 % ±5148 % ,与正
常对照组(17158 % ±614 %) 相比在统计学上有显著性差异( P < 01001) 。SVT 治疗8 周后反应性充血时肱动脉内径
的扩张程度为14168 % ±5105 % ,与治疗前相比明显改善( P < 01001) 。结论 应用CDFI 可以准确、简便、有效地评
价肱动脉血管内皮功能,对早期发现及评估动脉粥样硬化的发生等具有一定的临床价值。 |
| 英文摘要: |
| Objective To investigate the clinical applicant value of color Doppler flow imaging (CDFI) on evaluating the
brachial artery endothelial function. Methods 30 patients with primary hypercholesterolemia ( PHC) administered with
simvastatin(SVT) for 8 weeks. The changes of brachial artery intemal diameter under the reactive hyperaemia situation or
after taking nitroglycerin were evaluated by CDFI before and after treated with SVT respectively. Results The changes of
brachial artery diameter before administered with SVT in PHC patients in reactive hyperaemia condition were 3138 ±
5148 %. There was a statistically significant difference between experiment group and control group (17158 ±6147 %) ( P <
01001) . The changes of brachial artery diameter after treatment with SVT in reactive hyperaemia condition were 14168 ±
5105 %. There also was a statistically significant difference between before and after treated with SVT( P < 01001) . Conclusion It is a simple ,accurate and effective method to evaluate the brachial artery endothelial function with color Doppler
ultrasound. |
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