| 齐静,杜湘珂,王德航,谢敬霞.颞叶癫痫的1HMRS 和MRI 对比研究[J].中国医学影像技术,2000,16(2):103~105 |
| 颞叶癫痫的1HMRS 和MRI 对比研究 |
| Studies on Temporal Lobe Epilepsy by 1 HMRS and MRI |
| 投稿时间：1999-10-04 |
| DOI： |
| 中文关键词: 颞叶癫痫 海马 磁共振成像 质子波谱分析 |
| 英文关键词:Temporal lobe epilepsy Hippocampus Magnetic resonance imaging Magnetic resonance spectroscopy |
| 基金项目: |
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| 中文摘要: |
| 目的 通过对顽固性颞叶癫痫病人的质子波谱( 1 HMRS) 和磁共振成像(MRI) 研究,探讨这两种方法对
癫痫灶定位诊断的作用。方法 22 例无颞叶占位的癫痫病人和30 例健康志愿者分别进行了1HMRS 采集和MRI
扫描后海马结构定量研究,分析NAA/ Cr + Cho 和DHF 在癫痫组的改变及对癫痫组定侧定位的敏感性和特异性。
结果 1HMRS 可对16 例病人进行定侧诊断,并发现10 例有双侧颞叶病变。MRI 可准确判断10 例海马萎缩。结论
1HMRS 对颞叶癫痫定侧敏感性高于海马体积测量,并能发现双侧病变;MRI 海马结构定量发现海马硬化特异性较
高。 |
| 英文摘要: |
| Purpose To determine the relative utility of 1HMRS and MRI for presurgical lateralization of temporal lobe
epilepsy ( TL E) by the study of metabolic abnormalities and anatomical alterations in the brain of patients with TL E. Methods 1HMRS and MRI were performed on 22 patients with TLE of non-mass lesion origin and 30 healthy volunteers on
2.0 TMRI/ MRS system. The ratio of NAA/ Cr + Cho was measured and the difference of hippocampal formation (DHF)
was calculated. NAA/ Cr + Cho and DHF were analyzed for evaluation of the sensitivity and specificity of lateralizing seizure
origin. Results On the basis of the NAA/ Cr + Cho ratio ,we achieved lateralization in 17 cases ,10 cases showing bilateral
abnormalities with the ipilateral side more severe than the contralateral side. According to the 95 % normal reference range
DHF(-0119～0141) ,10 of these patients showed hippocampal atrophy. Conclusion 1HMRS was more sensitive than
MRI volumetric measurement in lateralizing seizure origin ,but MRI was more specific than 1HMRS. |
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