| 肖保军,李治安,杨娅,王新房,谢明星,刘俐,吕清.冠脉血流显像对照SPECT对心肌缺血冠脉储备功能的临床研究[J].中国医学影像技术,2000,16(1):0016~19 |
| 冠脉血流显像对照SPECT对心肌缺血冠脉储备功能的临床研究 |
| Clinical Research on Coronary Flow Reserve During Mycardial Ischemia :Compared with Single Photon Electronic Computer Tomotraphy ( SPECT) |
| 投稿时间：1999-10-07 |
| DOI： |
| 中文关键词: 超声心动图 彩色多普勒血流显像 冠脉血流储备 心肌缺血 高血压 |
| 英文关键词:Echocardiagraphy Color Doppler flow imaging Coronary flow reserve Myocardial ischemia Hypertension |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨经胸冠脉血流显像技术冠脉储备功能的测定诊断心肌缺血的可行性及临床价值。方法 61
名受试者均经ECT 静态心肌和运动心肌检查,依ECT 结果分为三组:A 组24 例,ECT 静态心肌和运动心肌均正常;
B 组19 例,静态心肌正常,运动心肌缺血;C 组18 例,静态心肌和运动心肌均缺血。依照ECT 示缺血心肌部位选择
相应的靶血管的远端,应用冠脉血流显像技术,测量潘生丁药物负荷试验前后靶血管远端舒张期峰值血流速度,以
及潘生丁药物负荷试验冠脉血流速度储备CVR 测值。另外,将其中的42 例原发性高血压患者依不同临床分级分为
二组: Ⅰ组27 例,为轻、中度高血压组; Ⅱ组15 例,为重度高血压。测量潘生丁药物负荷试验前后舒张期峰值血流速度及CVR 值。结果 ①随ECT 所示缺血程度的加重CVR 值逐渐降低。②随着高血压程度的加重,CVR 值逐渐降低。结论 本研究表明经胸冠脉血流速度储备CVR 测定对心肌缺血的诊断提供了重要的血流动力学指标。 |
| 英文摘要: |
| Objective The aim is to measure coronary flow reserve by transthoracic color Doppler coronary flow imaging and analyze the credibility and clinical value of this method in the diagnosis of myocardial ischemia. Methods 61 patients
were divided into three groups after according to the results of the examination by rest and exercise ECT : Group A including
24 patients with normal exercise by both rest and exercise imaging ; Group B including patients with myocardial ischemia by
positive exercise imaging and negative results by rest imaging ,and Group C 18 with positive results both at rest and after exercise ECT. The distal segments of the target artery which supply ischemic myocardium indicated by ECT were examined by
color Doppler coronary flow imaging. Peak diastolic flow velocities before and during infusion of dipyridamole and the ratio
were measured. In additon ,42 of 61 patients with essential hypertension were divided into subgroups :group Ⅰwith mild to
moderate hypertension ;group Ⅱwith severe hypertension. Peak diastolic flow velocity and CVR before and during infusion
of dipridamole were calculated. Results (1) CVR by transthorcic color Doppler coronary flow imaging decreased with the
severity of myocardial ischemia by ECT. (2) CVR were worsen graduately with the severity of hypertension. Conclusion
Transthoratic cononary flow imaging could provide hemodynamic indices for myocardial ischemia. |
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