| 方世明,薛杰,钱朝霞,陈调仙.乳腺X线摄影诊断乳腺癌的敏感性和特异性分析[J].中国医学影像技术,1999,15(7):493~495 |
| 乳腺X线摄影诊断乳腺癌的敏感性和特异性分析 |
| Assessing the Sensitivity and Specificity of Mammography to Breast Cancer |
| 投稿时间：1999-01-24 |
| DOI： |
| 中文关键词: 乳腺癌 乳腺X线摄影 敏感性 特异性 |
| 英文关键词:Breast cancer Mammography Sensitivity Specificity |
| 基金项目: |
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| 摘要点击次数: 1631 |
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| 中文摘要: |
| 目的 评价乳腺X线摄影诊断乳腺癌的准确性,探讨影响其敏感性和特异性的因素。方法 取经组织病理证实的443 例良恶性乳腺病变的术前乳腺片( 良性病变259 例,恶性病变184 例),根据乳腺X 线装置性能、投照位置、胶片、洗片机等技术特点不同将其分成两组：A 组(n = 163)和B组( n= 280).①A 组应用国产DGX MF 30钼靶摄影装置,仅有两侧乳腺侧位片；②B组采用美国BENNETT MF 150 乳腺摄影系统,有侧位和轴位片。然后由两位资深乳腺放射诊断医师分别采用盲法( 不参考临床资料仅根据乳腺片的影像特点作出诊断) 和综合法( 结合临床资料对乳腺片作出诊断) 对乳腺片进行分析辨别,最后将X 线分析结果与组织病理诊断作对照,根据有关真阳性、假阴性、真阴性及假阳性病例数,计算出相因的敏感性和特异性。结果 A 组的乳腺X 线摄影的敏感性和特异性分别为：盲法70.31% 和76.77 %,综合法78.13% 和83.83 % ;B组分别为：盲法81.67 % 和88.75 %,综合法89.17 % 和93.75 %,B组的乳腺X 线摄影的敏感性和特异性高于A 组 。 |
| 英文摘要: |
| Purpose To determine the accuracy of mammography in diagnosing breast cancer and assessed what have an effect on sensitivity and specificity.Methods 443 breast diseases with histopathological verfication (259 benign,184 malignant),which were divided into two groups:①group A, 163 cases were underwent mammography with shanghai DGX MF 30 medical systems,standard lateral mammograms were available only;②group B,280 cases were underwent mammography with BENNETT MF 150 medical systems,the standard lateral and craninoocaudal mammograms were available.The mammograms were identified blind (do not relate to clinical data) and combined clinical data by two special radiologists who were blinded as to whether the benign or malignant lesion.At last,all the interpretations of radiologists were then compared with the histopathologically confirmed diagnosis.Results For sensitivity and specificity of mammography to breast cancer in group A:the blinded interpretation was 70% and 77%,the combined interpretation was 78% and 84%;in group B:the blinded interpretation was 82% and 89%,the combined interpretation was 89% and 94%,respectively.For sensitivity and specificity,the combined interpretation was higher than the blinded and group A was higher than group B.Conclusion Variability and limitations in accuracy remain.However,high quality mammograms and the combined interpretation can enhance the radiologists’ ability to interpret mammograms with high sensitivity for detecting patients with cancer and high specificity for excluding patients without cancer.In order to mainatain the high quality mammograms,the strict technical standards and program for quality control is necessary. |
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