| 吴静,王萍,赵雪梅,王拥军,张立群.彩色超声多普勒及OXLDL检查联合诊断颈动脉粥样硬化病变的价值[J].中国医学影像技术,1999,15(6):442~444 |
| 彩色超声多普勒及OXLDL检查联合诊断颈动脉粥样硬化病变的价值 |
| Differential Diagnosis of Carotid Atherosclerosis by Color Doppler Flow Imaging and Plasma OXLDL |
| 投稿时间：1998-12-22 |
| DOI： |
| 中文关键词: 彩色超声多普勒显像 颈动脉粥样硬化 氧化修饰型低密度脂蛋白 |
| 英文关键词:CDFI CAS OXLDL |
| 基金项目: |
|
| 摘要点击次数: 957 |
| 全文下载次数: 659 |
| 中文摘要: |
| 目的研究彩色超声多普勒(CDFI)及血浆OXLDL水平在诊断颈动脉粥样硬化(CAS)病变中的价值。方法应用CDFI检查168例颈动脉(CA),以CA内膜厚度、斑块情况、狭窄程度的超声分级和病理学分型作为评价CAS硬化程度的指标。从中筛选出66例,分为CAS组和正常对照组,进行血脂、低密度脂蛋白(LDL)及氧化修饰型LDL(OXLDL)水平测定。CAS组再分为糖尿病DM(+)和DM(-)组。将所有结果逐一对比分析。结果CDFI检出阳性患者125例。CAS组OXLDL水平明显高于对照组(P<0001),具有显着性差异；DM(+)组显着高于DM(一)组(P<005).分析表明血浆OXLDL水平增高是致AS的危险因素之一。超声检查能发现早期临床无症状的CAS,并能够提示CAS斑块造成CA狭窄程度。结论CDFI与OXLDL检查联合应用可为预防CAS的形成,早期发现及治疗提供可靠的依据。 |
| 英文摘要: |
| Purpose To study the role of color Doppler flow imaging (CDFI) and plasma OX low-density lipoproteins (LDL) in CAS patients.Methods To estimate CAS,the carotid (CA) ultrasound examinations were performed by CDFI in 168 patients,classified into the various degrees according to pathology and stricture of ultrasound IMT's thickness,spot-types.Among them,66 patients were divided into CAS(+) and CAS(-),and their blood was examined for cholesterol (CHO),triglyceride (TG),plasma LDL and OXLDL.The CAS(+) group consists of Diabetes DM(+) and DM(-) patients.Results 125 cases were diagnosed as CAS by carotid CDFI.The plasma OXLDL levels of CAS(+) patients were significantly higher than CAS(-) ( P <0 001),DM(+) than DM(-) ( P <0 05).The analysis indicated that OXLDL was one of the main risk factors of CAS,meanwhile,non symptom,plaque and stricture degrees of CAS were able to be characterized early using CDFI.Conclusion The study demonstrated that combination use of these two examination strategies might be valuable to prevent the formation,early diagnosis and treatment of CAS. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
