| 洪楠,罗德馨,蒲永林,刘赓年,冯义濂.正常成人脑质子波谱临床研究[J].中国医学影像技术,1997,13(2):97~100 |
| 正常成人脑质子波谱临床研究 |
| In vivo Proton Magnetic Resonance Spectroscopic Study on Healthy Adult Human Brain |
| 投稿时间：1996-07-23 |
| DOI： |
| 中文关键词: 人脑 磁共振 质子 点解析波谱 定量 波谱 N-乙酰天门冬氨酸 肌酸 胆碱 乳酸 |
| 英文关键词:Human brain Magnetic resonance Proton PRESS Quantification Spectroscopy N acetyl aspartate Creatine Choline Lactate |
| 基金项目: |
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| 摘要点击次数: 2198 |
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| 中文摘要: |
| 作者在2.0T条件下,用标准头部线圈作为发射和接收线圈,用PRESS序列对健康人脑进行活体质子波谱临床研究,并以总肌酸为内标准计算其它代谢产物的绝对含量。在基底结区,NAA和Cho的绝对含量分别为15.113±2.160mmol和2.664±0.501mmol,作者认为本方法可以比较准确地估算代谢产物的绝对含量,具有较大的临床意义。 |
| 英文摘要: |
| he ability of absolute quantification of major metabolite concentrations in the adult human brain in vivo by 1H MRS using total creatine as an endogenous standard was tested. The study was performed at 2.0T with use of standard head coil and PRESS sequence. Calculated average concentrations of NAA and Cho in the ganglion region of the brain in 18 healthy volunteers were 15.113± 2.160 mmol and 2.664±0.501mmol. The results indicate that the method presented offers resonable estimation of metabolite concentrations in the brain in vivo and therefore is useful in clinical research. |
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